DESCRIPTION:Dexdomitor is a sedative and analgesic that eases moderately or mildly painful, non-invasive procedures, minor surgical procedures, and clinical procedures or exams.
Key Benefits: This medication is an alpha-2 adrenoceptor antagonist. This synthetic drug is incredibly selective and effective on these adrenoreceptors, which has an inhibitory effect on the release of noradrenaline.
Formulated For: Intended for cats and dogs.
How is Medication Given?
In cats, this medication delivers analgesia and sedation when intramuscularly administered at a dosage rate of 40 mcg per kg of body weight. In dogs, analgesia and sedation are produced with an intramuscular dose of 500 mcg per m2, or at an intravenous dosage rate of 375 mcg per m2. For pre-anesthesia dosing, intramuscularly administer 125 to 375 mcg per m2. Pre-anesthetic should depend upon the severity and duration of the procedure, along with the anesthetic regimen. The mcg per kg dosage rate decreases as the dog&339;s body weight increases, so a dog who weighs 2 kg would receive a dose of 28 mcg per kg, while a dog weighing 80 kg would receive a dose of 9 mcg per kg. This medication should not be used in dogs under 2 kg because it cannot be accurately dosed. Maximum effect should take place within 10 to 15 minutes, with duration depending upon the dose (but typically falling within the 30- to 180-minute range). Repeat dosing as needed. When using for pre-anesthetic purposes, subsequent anesthetic doses may be reduced by up to 60%.
What Results Can I Expect: Dexdomitor:
Offers dose-dependent sedation depth and duration Provides potent analgesia with a rapid onset Relaxes the muscles Effectively reduces hypersensitivity to noise Provides smooth, predictable recovery when used concomitantly with Antisedan
What Form Does Medication Come In? Injectable
Dose and Administration: Sold in a vial containing 10 mL.
Possible Side Effects: Fasted or fed cats may experience vomiting. Rarely, cats may experience:
Fatigue Anorexia Cystitis Peripheral Vascular Disorder
Potential adverse reactions in dogs include:
Decreased Respiratory Rate Hypothermia
Precautions:
Administer cautiously to animals with cardiovascular, respiratory, liver, or kidney disease, or those in poor health. Concomitant use of other CNS depressants will likely potentiate the depressant effects of one or both drugs. Adjust dosages as needed. Antisedan is used to reverse Dexdomitor's effects. Using atropine, glycopyrrolate, or other anticholinergics to treat bradycardia (following medetomidine use or concomitantly) can produce severe cardiovascular problems. Not proven safe for use in pregnant animals. Never administer concomitantly with a sympathomimetic amine.
Storage Recommendations: Store at 59-86 degrees F (15-30 degrees C ). Shield from freezing.
In Case of Overdose: Contact the nearest emergency pet clinic.
