Spot On

(35 results)
Frontline Plus Cat Flea & Tick Treatment
3 sizes
(546)
$39.99 - $96.99
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Advantage® II Over 9 lbs Cat Flea Prevention & Treatment
4 sizes
(689)
$16.99 - $70.99
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Advantage® II 5-9 lbs Cat Flea Prevention & Treatment
4 sizes
(386)
$16.99 - $68.99
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Advantage® II 2-5 lbs Kitten Flea Prevention & Treatment
(54)
$33.59
$34.99
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Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(1)
$14.99
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Revolution Plus for Cats 11.1-22 lbs Green - 3 or 6 Month Supply
2 sizes
(17)
$91.09 - $159.29
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Revolution Plus for Cats 5.6-11 lbs Orange - 3 or 6 Month Supply
2 sizes
(13)
$85.79 - $154.49
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Cheristin, Cat Flea and Tick Treatment and Prevention
3 sizes
(1)
$16.69 - $78.69
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PetArmor® Plus for Cats Over 1.5 lbs Flea & Tick Spot On Treatment
2 sizes
(999)
$24.99 - $39.99
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Advantage® XD Over 9 lbs Large Cat Flea Prevention & Treatment
3 sizes
(744)
$34.99 - $95.99
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NextStar® Flea & Tick Prevention for Cats
2 sizes
(172)
$35.99 - $52.99
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Advantage® XD 1.8-9 lbs Small Cat Flea Prevention & Treatment
3 sizes
(611)
$34.99 - $95.99
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Advantage Topical Cat Flea Treatment and Prevention For Large Cats Over 9 lbs.
(1)
$14.99
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Bravecto Topical Solution for Cats, 6.2 - 13.8 lbs 250 mg Blue
(5)
$72.99
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Bravecto Plus Topical Solution for Cats
(1)
$51.99 - $52.99
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Advantage Multi for Cats 9.1-18 lbs
2 sizes
(1)
$19.99 - $119.80
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Revolution Topical for Cats 5.1-15 lbs Blue
3 sizes
(2)
$104.49 - $378.99
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Only Natural Pet Flea & Tick Spot On 3 count
(1)
$19.99
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Senergy (selamectin) Topical for Cats 5.1 - 15 lbs, 3 doses
(1)
$49.39
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Selarid (selamectin) Topical for Cats 5.1-15 lbs, Blue (6 Month Supply)
(0)
$71.99
$92.59
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Bravecto Topical Solution for Cats, 13.8 - 27.5 lbs 500 mg Purple
(1)
$73.99
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Only Natural Pet® Cat Flea, Tick & Mosquito Treatment
(443)
$19.99
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Liquid-Vet® Feline Flea & Tick+Support Formula
(0)
$11.49
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+ 1 more
Vetality Naturals Flea & Tick Topicals for Cats
(7)
$12.89
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+ 1 more
Senergy (selamectin) Topical for Cats 15.1 - 22 lbs, 3 doses
(0)
$50.59
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Senergy (selamectin) Topical for Kittens and Puppies Up to 5 lbs, 3 doses
(0)
$42.89
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Selarid (selamectin) Topical for Cats 15.1-22 lbs, Taupe (6 Month Supply)
(0)
$73.49
$94.79
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Selarid (selamectin) Topical for Kittens/Puppies Up to 5 lbs, Mauve (3 Month Supply)
(0)
$32.49
$43.59
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Advantage Multi for Cats 5.1-9 lbs
2 sizes
(2)
$19.79 - $118.69
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Revolution Topical for Cats 15.1-22 lbs Taupe
3 sizes
(1)
$112.79 - $388.99
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Revolution Topical for Puppies and Kittens up to 5 lbs Pink
(0)
$71.99
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Bravecto Topical Solution for Cats, 2.6 - 6.2 lbs 112.5 mg Green
(0)
$71.99
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Advantage Multi for Cats 2-5 lbs, 3 Month Supply
(0)
$74.29
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Revolution Topical for Puppies and Kittens up to 5 lbs Pink - 3 Month or 6 Month Supply
(0)
$71.39
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Sergeant's Guardian Flea and Tick Topical for Cats - 6lbs and over - 3 Month Supply
(4)
$5.19
$9.99
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  1. 1
Fleas and ticks are absolutely no fun for you or your pet cat. They can cause issues for your pet when not addressed. If your cat has fleas or ticks, you should talk to your vet about the best options to help get rid of them. Pet parents can find a great selection of cat flea topical drops and cat flea spot-ons at PetSmart. We want to help you protect your cat from fleas and ticks. 
Our selection of cat flea/tick prevention products extends far past only flea and tick topical drops for cats. We also carry: 
You are sure to find what you need to help get rid of fleas or protect your cats from them at PetSmart. Need other cat supplies while you’re here? We have you covered. 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.