Enjoy every outing

Get flea & tick preventions, treatments & tips for your kitty

Flea & Tick

(84 results)
Seresto® Vet-Recommended 8-Month Collar, Flea & Tick Prevention for Cats
2 sizes
(917)
$59.99 - $115.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Advantage® II Flea Prevention & Treatment for Large Cats over 9 lbs, Monthly Doses
3 sizes
(718)
$19.99 - $69.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Capstar™ Fast-Acting Oral Flea Treatment for Cats 2-25 lbs
2 sizes
(665)
$43.19 - $70.19
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Frontline Plus Flea & Tick Spot Treatment for Cats, 1.5 lbs and over
3 sizes
(560)
$40.98 - $98.98
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Advantage Topical Cat Flea Treatment and Prevention For Large Cats Over 9 lbs.
(292)
$14.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(192)
$14.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
PetArmor® Home Flea & Tick Home & Carpet Spray, 16 oz
(596)
$8.79
$10.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Revolution Plus for Cats 5.6-11 lbs Orange - 3 or 6 Month Supply
2 sizes
(14)
$91.74 - $165.24
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
Revolution Plus for Cats 11.1-22 lbs Green - 3 or 6 Month Supply
2 sizes
(19)
$97.38 - $170.34
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
Advantage® II Flea Prevention & Treatment for Small Cats 5-9 lbs, Monthly Doses
4 sizes
(400)
$19.99 - $69.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Cheristin, Cat Flea and Tick Treatment and Prevention
3 sizes
(2)
$17.99 - $84.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 1 more
Advantage® XD Flea Prevention & Treatment for Large Cats over 9 lbs, 2 Months Protection per Dose
3 sizes
(748)
$37.99 - $99.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
NextStar® Flea & Tick Waterproof Topical Prevention for Cats over 3.5 lbs
2 sizes
(177)
$34.99 - $52.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
NexGard COMBO Topical Solution for Cats - 5.6-16.5 lbs, Yellow Box
3 sizes
(4)
$38.69 - $182.69
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
PetArmor® CapAction Fast-Acting Oral Flea Treatment for Cats 2-25 lbs, 6 doses
(54)
$31.49
$34.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 1 more
PetArmor® Plus Flea & Tick Prevention for Cats over 1.5 lbs, Spot On Treatment
2 sizes
(1020)
$26.14 - $42.27
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
K9 Advantix® Flea, Tick & Mosquito Prevention for Extra Large Dogs 55+ lbs, Monthly Dose Treatment
(147)
$14.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Advantage® II Flea Prevention & Treatment for Cats and Kittens 2-5 lbs, Monthly Doses
(58)
$33.59
$34.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Whisker City® Pet Flea Comb
(130)
$8.99
Free Same-Day Delivery, No Order Minimum!
Sign In & Enjoy Free Shipping Over $49
Credelio CAT Flea & Tick Prevention & Treatment for Cats 4.1–17 lbs | 1, 3, or 6 Month Supply
3 sizes
(0)
$25.55 - $138.31
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
Advantage® XD Flea Prevention & Treatment for Small Cats 1.8-9 lbs, 2 Months Protection per Dose
3 sizes
(613)
$37.99 - $99.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Bravecto Topical Solution for Cats, 6.2 - 13.8 lbs 250 mg Blue
(5)
$72.99
Sign In & Enjoy Free Shipping Over $49
Advantage Multi Cat 5-in-1 Heartworm Prevention | Kills Fleas | Cats 9.1-18 lbs. | 6-Month Supply
2 sizes
(1)
$19.99 - $129.79
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Cats 5.1-15 lbs Blue
3 sizes
(2)
$114.97 - $416.22
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
PetArmor® Flea & Tick Collar for Cats
(134)
$12.99
$14.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
PetArmor® Extend Flea & Tick Treatment & Prevention Collar for Cats, 8 Months of Protection
(224)
$39.99
$44.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save $5 on any Pet Armor Extended Release Collar
+ 2 more
Only Natural Pet Easy Defense Flea &Tick Cat Collar
(127)
$14.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
TropiClean Natural Flea + Tick No-Rinse Cat Shampoo - 7.4 oz Bottle
(9)
$16.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Wondercide Cedarwood Scent Home & Pet Flea & Tick Spray
(3299)
$26.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Wondercide Flea & Tick Shampoo For Dogs & Cats
(245)
$19.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Wondercide Peppermint Scent Home & Pet Flea & Tick Spray
(3131)
$26.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Wondercide Lemongrass Scent Home & Pet Flea & Tick Spray
2 sizes
(3806)
$13.99 - $26.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Senergy (selamectin) Topical for Cats 5.1 - 15 lbs, 3 doses
(1)
$49.39
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
Bravecto Plus Topical Solution for Cats
(2)
$51.99 - $52.99
Sign In & Enjoy Free Shipping Over $49
Selarid (selamectin) Topical for Cats 5.1-15 lbs, Blue (6 Month Supply)
(0)
$71.99
$92.59
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Puppies and Kittens up to 5 lbs Pink - 3 Month Supply
(0)
$76.30
Save 40% on your first Prescription Flea and Tick Autoship order!
Sign In & Enjoy Free Shipping Over $49
PetArmor® Flea & Tick Cat Shampoo, Coconut Berry scent, 12 oz
(30)
$8.99
$11.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Only Natural Pet® EasyDefense™ Flea & Tick Home Spray
(170)
$18.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Vet's Best® Flea + Tick Home Spray
(134)
$15.48
$17.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
Only Natural Pet® EasyDefense™ All-in-One Flea Remedy Powder
(608)
$14.99
Buy 1, get the 2nd 25% OFF ALL flea & tick products
Save 40% Off First Autoship Order on Flea and Tick Products
+ 2 more
  1. 1
  2. 2
  3. 3

Comprehensive Cat Flea Treatment Solutions at PetSmart

Flea infestations can be a nuisance for both cats and their owners, but effective flea treatment solutions are available to help protect your feline friends. At PetSmart, we offer a full range of cat flea treatment options, including flea medicine for cats, flea shampoos, flea sprays, and vet-recommended solutions like Advantage II for cats. These treatments are designed to eliminate fleas quickly and efficiently, ensuring both your pet's comfort and your home's safety.

Help Your Cat Get Relief Fast and Stop Fleas from Spreading

If your cat has fleas, it’s important to act quickly. Fleas don’t just make your cat itchy, they can spread fast, lay eggs in your home, and become a bigger problem over time. Catching and treating an outbreak early helps keep your cat comfortable and your home protected.
One fast option many pet parents use is an oral flea tablet. These tablets start working within 30 minutes to kill adult fleas and give your cat quick relief. They're a great way to stop the problem right away before switching to a longer-lasting treatment.
After that, you can use other products like monthly topical treatments, flea collars, or sprays to keep fleas from coming back. No matter which option you choose, treating your cat and home right away is the best way to stop fleas before they get worse.

Types of Flea Treatment Options

  • Flea Shampoo for Cats: Cleanse and protect your pet's coat with specially formulated shampoos that target fleas and larvae.
  • Flea Spray for Cats: Convenient for on-the-go protection, sprays help guard your pet and indoor areas against fleas and ticks.
  • Flea Powder for Cats: Easy-to-use powders that offer a dust-free treatment experience for your pet's skin and fur.
  • Vet-Recommended Flea Treatments: Trust in vet recommended flea treatments for cats for reliable and effective protection.
  • Advantage II for Cats: A long-lasting topical treatment that offers monthly protection by killing fleas through contact.
Browse PetSmart's selection of flea and tick treatments for cats and keep your pet safe from pests all year round. Look for options that suit your cat's lifestyle, and enjoy the convenience of curbside pickup, Autoship, or same-day delivery to get started on protecting your pet today.

Frequently Asked Questions (FAQs)

What is the most effective flea treatment for cats?

The most effective flea treatments often include options like Advantage II or Frontline, which are topicals applied monthly to prevent and kill fleas on cats.

What is the fastest way to kill cat fleas?

For quick action, Capstar tablets can be administered, which begin to kill adult fleas within 30 minutes, offering fast relief from active infestations.

What to do if an indoor cat has fleas?

Treat your cat with a proven flea treatment such as Advantage II or Frontline. Thoroughly clean your home environment to eliminate lingering fleas, focusing on fabric surfaces, carpets, and pet bedding.

What is the best flea treatment for cats without a vet prescription?

Over-the-counter options such as Advantage II and Frontline Plus are available without a prescription and effectively manage flea infestations.