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  • 3 Sizes

    Frontline Plus Cat Flea & Tick Treatment

    Discounted Price $40.99 - 93.99 Old Price $41.99 - 94.99
    (279)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 3 Sizes

    Frontline Plus Flea & Tick Dog Treatment 5-22 lbs

    Discounted Price $40.99 - 93.99 Old Price $41.99 - 94.99
    (403)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 3 Sizes

    Frontline Plus Flea & Tick Dog Treatment 45-88 lbs

    Discounted Price $40.99 - 93.99 Old Price $41.99 - 94.99
    (378)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 3 Sizes

    Frontline Plus Flea and Tick Dog Treatment 23-44 lbs

    Discounted Price $40.99 - 94.99 Old Price $41.99 - 94.99
    (333)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 3 Sizes

    Frontline Plus Flea & Tick Dog Treatment 89-132 lbs

    Discounted Price $40.99 - 93.99 Old Price $41.99 - 94.99
    (330)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs, 41-80lbs, 1 Month, Waterproof

    Discounted Price $46.99 - 82.99 Old Price $47.99 - 83.99
    (932)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs, 11-20lbs, 1 Month, Waterproof

    Discounted Price $46.99 - 82.99 Old Price $47.99 - 83.99
    (942)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs, 21-40lbs, 1 Month, Waterproof

    Discounted Price $46.99 - 82.99 Old Price $47.99 - 83.99
    (928)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs, 81-120lbs, 1 Month, Waterproof

    Discounted Price $46.99 - 82.99 Old Price $47.99 - 83.99
    (930)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Gold Flea & Tick Treatment for Medium Dogs, 23-44 lbs

    Discounted Price $54.99 - 94.99 Old Price $56.99 - 94.99
    (2)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Gold Flea & Tick Treatment for Extra Large Dogs, 89-132 lbs

    Discounted Price $54.99 - 94.99 Old Price $56.99 - 94.99
    (3)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Gold Flea & Tick Treatment for Small Dogs, 5-22 lbs

    Discounted Price $54.99 - 94.99 Old Price $56.99 - 94.99
    (4)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs, 5-10lbs, 1 Month, Waterproof

    Discounted Price $46.99 - 82.99 Old Price $47.99 - 83.99
    (929)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Gold Flea & Tick Spot Treatment for Cats, over 1.5 lbs

    Discounted Price $54.99 - 94.99 Old Price $56.99 - 94.99
    (11)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!
  • 2 Sizes

    Frontline Gold Flea & Tick Treatment for Large Dogs, 45-88 lbs

    Discounted Price $54.99 - 94.99 Old Price $56.99 - 94.99
    (4)

    Save 35% On Your First Autoship Order!

    For every Same-Day Delivery order, we'll donate $1 and DoorDash will donate $1 to PetSmart Charities!

FRONTLINE® flea treatment for dogs and cats works quickly to kill fleas, ticks, and lice. And, when used monthly, it can help keep pests at bay by breaking the flea life cycle and controlling tick infestations. Formulated for dogs, puppies, cats, and kittens ages eight weeks and older, FRONTLINE Plus can help protect dogs and cats at every stage of life from harmful parasites. Shop PetSmart’s collection of FRONTLINE flea treatment for dogs and cats to help protect your pet from those pesky pests.

Shop PetSmart’s collection of Frontline flea and tick treatment for dogs and cats in stores or online. Looking for other dog supplies or cat products? We also carry other brands and options of flea and tick treatments for dogs like flea and tick sprays and spot on flea drops. We haven’t forgotten our feline friends! We also have flea sprays and flea drops for cats. Check out all of our flea and tick treatments for cats and dogs at your neighborhood PetSmart.

PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see what items are eligible.

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