Spot Ons

(60 results)
K9 Advantix® II Over 55 lbs Dog Flea & Tick Treatment
4 sizes
(302)
$18.99 - $79.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Frontline Plus Flea & Tick Dog Treatment 5-22 lbs
3 sizes
(548)
$39.99 - $96.99
Save 40% on your first Autoship Order of Frontline
2X points (4% back in savings) on flea and tick purchases
+ 2 more
K9 Advantix® II 21-55 lbs Dog Flea & Tick Treatment
4 sizes
(263)
$18.99 - $79.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Frontline Plus Flea & Tick Dog Treatment 45-88 lbs
3 sizes
(596)
$39.99 - $96.99
Save 40% on your first Autoship Order of Frontline
2X points (4% back in savings) on flea and tick purchases
+ 2 more
K9 Advantix® II 11-20 lbs Dog Flea & Tick Treatment
4 sizes
(256)
$18.99 - $79.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Frontline Plus Flea and Tick Dog Treatment 23-44 lbs
3 sizes
(365)
$39.99 - $96.99
Save 40% on your first Autoship Order of Frontline
2X points (4% back in savings) on flea and tick purchases
+ 2 more
Frontline Plus Flea & Tick Dog Treatment 89-132 lbs
3 sizes
(502)
$39.99 - $96.99
Save 40% on your first Autoship Order of Frontline
2X points (4% back in savings) on flea and tick purchases
+ 2 more
K9 Advantix® II Under 10 lbs Dog Flea & Tick Treatment
4 sizes
(236)
$18.99 - $79.98
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs 11-20 Lbs
2 sizes
(940)
$49.99 - $89.99
Save 40% on your first Autoship Order of Frontline
2X points (4% back in savings) on flea and tick purchases
Revolution Topical for Dogs 10.1-20 Brown - 3 Month or 6 Month Supply
2 sizes
(3)
$94.49 - $166.39
Sign In & Enjoy Free Shipping Over $49
Advantage® II Over 55 lbs Dog Flea & Lice Treatment
2 sizes
(65)
$50.99 - $66.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
PetArmor® Plus for Dogs 45-88 lbs Flea & Tick Spot On Treatment
2 sizes
(1820)
$24.99 - $39.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
PetArmor® Plus for Dogs 5-22lbs Flea & Tick Spot On Treatment
2 sizes
(1862)
$24.99 - $39.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
NextStar® Flea & Tick Prevention for Medium Dogs 23-44 lbs
2 sizes
(372)
$34.99 - $52.99
10X points (20% back in savings) on NextStar & CapStar flea & tick products
2X points (4% back in savings) on flea and tick purchases
NextStar® Flea & Tick Prevention for Large Dogs 45-88 lbs
2 sizes
(374)
$34.99 - $52.99
10X points (20% back in savings) on NextStar & CapStar flea & tick products
2X points (4% back in savings) on flea and tick purchases
NextStar® Flea & Tick Prevention for Small Dogs 5-22 lbs
2 sizes
(374)
$34.99 - $52.99
10X points (20% back in savings) on NextStar & CapStar flea & tick products
2X points (4% back in savings) on flea and tick purchases
Advantage Multi Topical for Dogs 55.1-88 lbs Blue
4 sizes
(1)
$21.79 - $260.69
Sign In & Enjoy Free Shipping Over $49
Advantage Multi Topical for Dogs 20.1-55 lbs Red
4 sizes
(1)
$21.69 - $259.49
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Dogs 40.1-85 Teal - 3 Month or 6 Month Supply
2 sizes
(1)
$97.19 - $175.49
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Dogs 20.1-40 Red  - 3 Month or 6 Month Supply
2 sizes
(1)
$96.19 - $175.49
Sign In & Enjoy Free Shipping Over $49
Advantage® II 21-55 lbs Dog Flea & Lice Treatment
2 sizes
(54)
$50.99 - $66.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Advantage® II 11-20 lbs Dog Flea & Lice Treatment
2 sizes
(55)
$50.99 - $66.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
PetArmor® Ear Mite & Tick Treatment
(54)
$5.49
$8.29
Extra 20% off online only with code SAVE20, see terms
Free Same-Day Delivery, No Order Minimum!
+ 1 more
NextStar® Flea & Tick Prevention for Extra-Large Dogs 89-132 lbs
2 sizes
(373)
$34.99 - $52.99
10X points (20% back in savings) on NextStar & CapStar flea & tick products
2X points (4% back in savings) on flea and tick purchases
K9 Advantix® Classic 55+ lbs Dog Flea & Tick Treatment
(1)
$14.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
K9 Advantix® Classic 21-55 lbs Dog Flea & Tick Treatment
(0)
$14.99
2X points (4% back in savings) on flea and tick purchases
Save 35% On Your First Autoship Order!
Bravecto Topical Solution for Dogs
(1)
$64.99 - $67.99
Sign In & Enjoy Free Shipping Over $49
Advantage Multi Topical for Dogs 9.1-20 lbs Teal
4 sizes
(5)
$21.49 - $256.99
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Dogs 5.1-10 Purple - 3 Month or 6 Month Supply
2 sizes
(0)
$91.29 - $161.99
Sign In & Enjoy Free Shipping Over $49
Advantage Multi Topical for Dogs 3-9 lbs Green
4 sizes
(5)
$21.39 - $255.79
Sign In & Enjoy Free Shipping Over $49
Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs 81-120 Lbs
2 sizes
(922)
$49.99 - $89.99
Save 35% On Your First Autoship Order!
PetArmor® Plus for Dogs 89-132 lbs Flea & Tick Spot On Treatment
2 sizes
(1777)
$24.99 - $39.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
PetArmor® Plus for Dogs 23-44 lbs Flea & Tick Spot On Treatment
2 sizes
(1807)
$24.99 - $39.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Only Natural Pet® EasyDefense™ Herbal Dog Flea, Tick & Mosquito Treatment
3 sizes
(610)
$19.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Advantage® II 3-10 lbs Dog Flea & Lice Treatment
2 sizes
(68)
$50.99 - $66.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Sergeant's Guardian Flea & Tick Topical for Dogs 7-32 lbs
(0)
$5.99
2X points (4% back in savings) on flea and tick purchases
Sign In & Enjoy Free Shipping Over $49
Sergeant's Guardian Flea & Tick Topical for Dogs 33-66 lbs
(0)
$4.89
$5.99
2X points (4% back in savings) on flea and tick purchases
Sign In & Enjoy Free Shipping Over $49
Sergeant's Guardian Flea & Tick Topical for Dogs over 66 lbs
(0)
$5.99
2X points (4% back in savings) on flea and tick purchases
Sign In & Enjoy Free Shipping Over $49
Liquid-Vet® K9 Flea & Tick + Support Formula
(0)
$12.99
2X points (4% back in savings) on flea and tick purchases
Sign In & Enjoy Free Shipping Over $49
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Fleas are no fun for your dog or for you. They can cause issues for your pet when not addressed. If your dog has fleas or ticks, you should talk to your vet about the best options to help get rid of them. Pet parents looking for dog flea spot-ons or topical flea treatments for dogs can find what they need at PetSmart. We want to help you give your dog the best care with the best products. 
 
Our selection of dog flea prevention products includes options like: 
 
You can find everything you need to care for your pup at PetSmart. Need other dog supplies while you’re here? We have you covered. 
 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.