Spot Ons

(57 results)
K9 Advantix® II Over 55 lbs Dog Flea & Tick Treatment
4 sizes
(300)
$18.99 - $79.98
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K9 Advantix® II 21-55 lbs Dog Flea & Tick Treatment
4 sizes
(255)
$18.99 - $79.98
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Frontline Plus Flea & Tick Dog Treatment 45-88 lbs
3 sizes
(594)
$39.99 - $96.99
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Frontline Plus Flea & Tick Dog Treatment 5-22 lbs
3 sizes
(544)
$39.99 - $96.99
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K9 Advantix® II 11-20 lbs Dog Flea & Tick Treatment
4 sizes
(256)
$18.99 - $79.98
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Frontline Plus Flea and Tick Dog Treatment 23-44 lbs
3 sizes
(365)
$39.99 - $96.99
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K9 Advantix® II Under 10 lbs Dog Flea & Tick Treatment
4 sizes
(236)
$18.99 - $79.98
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Frontline Shield Extra Strength Flea & Tick Spot Treatment for Dogs
2 sizes
(938)
$49.99 - $89.99
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Frontline Plus Flea & Tick Dog Treatment 89-132 lbs
3 sizes
(500)
$39.99 - $96.99
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Revolution Topical for Dogs 10.1-20 Brown - 3 Month or 6 Month Supply
2 sizes
(3)
$94.49 - $166.39
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PetArmor® Plus for Dogs 45-88 lbs Flea & Tick Spot On Treatment
2 sizes
(1820)
$24.99 - $39.99
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PetArmor® Plus for Dogs 5-22lbs Flea & Tick Spot On Treatment
2 sizes
(1862)
$24.99 - $39.99
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Advantage® II Over 55 lbs Dog Flea & Lice Treatment
2 sizes
(65)
$50.99 - $66.99
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Advantage Multi Topical for Dogs 9.1-20 lbs Teal
4 sizes
(4)
$21.49 - $256.99
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Revolution Topical for Dogs 40.1-85 Teal - 3 Month or 6 Month Supply
2 sizes
(1)
$97.19 - $175.49
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Revolution Topical for Dogs 20.1-40 Red  - 3 Month or 6 Month Supply
2 sizes
(1)
$96.19 - $175.49
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Revolution Topical for Dogs 5.1-10 Purple - 3 Month or 6 Month Supply
2 sizes
(0)
$91.29 - $161.99
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Advantage® II 21-55 lbs Dog Flea & Lice Treatment
2 sizes
(54)
$50.99 - $66.99
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Advantage® II 11-20 lbs Dog Flea & Lice Treatment
2 sizes
(55)
$50.99 - $66.99
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PetArmor® Ear Mite & Tick Treatment
(53)
$5.49
$8.29
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K9 Advantix® Classic 55+ lbs Dog Flea & Tick Treatment
(1)
$14.99
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Bravecto Topical Solution for Dogs
(0)
$64.99 - $67.99
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Advantage Multi Topical for Dogs 55.1-88 lbs Blue
4 sizes
(1)
$21.79 - $260.69
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+ 1 more
Advantage Multi Topical for Dogs 20.1-55 lbs Red
4 sizes
(0)
$21.69 - $259.49
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Advantage Multi Topical for Dogs 3-9 lbs Green
4 sizes
(5)
$21.39 - $255.79
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PetArmor® Plus for Dogs 89-132 lbs Flea & Tick Spot On Treatment
2 sizes
(1777)
$24.99 - $39.99
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PetArmor® Plus for Dogs 23-44 lbs Flea & Tick Spot On Treatment
2 sizes
(1807)
$24.99 - $39.99
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Only Natural Pet® EasyDefense™ Herbal Dog Flea, Tick & Mosquito Treatment
3 sizes
(610)
$19.99
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Advantage® II 3-10 lbs Dog Flea & Lice Treatment
2 sizes
(68)
$50.99 - $66.99
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NextStar® Flea & Tick Prevention for Extra-Large Dogs 89-132 lbs, 6 Count
(0)
$52.99
$62.99
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NextStar® Flea & Tick Prevention for Medium Dogs 23-44 lbs, 6 Count
(0)
$52.99
$62.99
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NextStar® Flea & Tick Prevention for Large Dogs 45-88 lbs, 6 Count
(0)
$52.99
$62.99
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NextStar® Flea & Tick Prevention for Small Dogs 5-22 lbs, 6 Count
(0)
$52.99
$62.99
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Sergeant's Guardian Flea & Tick Topical for Dogs 7-32 lbs
(0)
$5.99
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Sergeant's Guardian Flea & Tick Topical for Dogs 33-66 lbs
(0)
$4.89
$5.99
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Sergeant's Guardian Flea & Tick Topical for Dogs over 66 lbs
(0)
$5.99
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K9 Advantix® Classic 21-55 lbs Dog Flea & Tick Treatment
(0)
$14.99
Save 35% On Your First Autoship Order!
Liquid-Vet® K9 Flea & Tick + Support Formula
(0)
$12.99
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Vetality Naturals Flea & Tick Topicals for Dogs
(78)
$11.99
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Senergy (selamectin) Topical for Dogs 85.1 - 130 lbs, 3 doses
(0)
$67.99
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Fleas are no fun for your dog or for you. They can cause issues for your pet when not addressed. If your dog has fleas or ticks, you should talk to your vet about the best options to help get rid of them. Pet parents looking for dog flea spot-ons or topical flea treatments for dogs can find what they need at PetSmart. We want to help you give your dog the best care with the best products. 
 
Our selection of dog flea prevention products includes options like: 
 
You can find everything you need to care for your pup at PetSmart. Need other dog supplies while you’re here? We have you covered. 
 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.