Spot On

(38 results)
Advantage® II Flea Prevention & Treatment for Large Cats over 9 lbs, Monthly Doses
3 sizes
(872)
$19.99 - $55.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Frontline Plus Flea & Tick Spot Treatment for Cats, 1.5 lbs and over
3 sizes
(576)
$32.78 - $79.18
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Advantage® II Flea Prevention & Treatment for Small Cats 5-9 lbs, Monthly Doses
4 sizes
(487)
$19.99 - $55.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
PetArmor® Plus Flea & Tick Prevention for Cats over 1.5 lbs, Spot On Treatment
2 sizes
(1022)
$26.12 - $31.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Advantage Topical Cat Flea Treatment and Prevention For Large Cats Over 9 lbs.
(298)
$14.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(198)
$14.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Revolution Plus for Cats 11.1-22 lbs Green - 3 or 6 Month Supply
2 sizes
(20)
$97.38 - $170.34
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Revolution Plus for Cats 5.6-11 lbs Orange - 3 or 6 Month Supply
2 sizes
(14)
$91.74 - $165.24
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Cheristin, Cat Flea and Tick Treatment and Prevention
3 sizes
(39)
$17.99 - $84.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Advantage® XD Flea Prevention & Treatment for Large Cats over 9 lbs, 2 Months Protection per Dose
3 sizes
(752)
$37.99 - $99.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
NextStar® Flea & Tick Waterproof Topical Prevention for Cats over 3.5 lbs
2 sizes
(180)
$34.99 - $42.39
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Advantage® XD Flea Prevention & Treatment for Small Cats 1.8-9 lbs, 2 Months Protection per Dose
3 sizes
(613)
$37.99 - $99.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Bravecto Plus Topical Solution for Cats, 6.2-13.8 lb (Blue), 1 Dose,  2-Month Supply
(0)
$55.99
5X points (10% back in savings) on ALL cat products
Sign In & Enjoy Free Shipping Over $49
Advantage® II Flea Prevention & Treatment for Cats and Kittens 2-5 lbs, Monthly Doses
(58)
$33.59
$34.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Bravecto Topical Solution for Cats, 6.2 - 13.8 lbs 250 mg Blue
(5)
$76.99
5X points (10% back in savings) on ALL cat products
Sign In & Enjoy Free Shipping Over $49
Advantage Multi Cat 5-in-1 Heartworm Prevention - Kills Fleas - Cats 9.1-18 lbs. - 6-Month Supply
2 sizes
(1)
$19.97 - $129.79
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Revolution Topical for Cats 5.1-15 lbs Blue
3 sizes
(2)
$114.97 - $416.22
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Only Natural Pet Flea & Tick Spot On 3 count
(153)
$19.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 2 more
Senergy (selamectin) Topical for Cats 5.1 - 15 lbs, 3 doses
(1)
$49.34
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Selarid (selamectin) Topical for Cats 5.1-15 lbs, Blue (6 Month Supply)
(0)
$71.91
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Vet's Best Flea & Tick Cat Waterless Bath - Natural Spot Treatment - Cotton Spice Scent - 5 FL OZ
(1)
$15.01
$16.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
Liquid-Vet® Feline Flea & Tick+Support Formula
(0)
$11.49
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Vetality Naturals Flea & Tick Topicals for Cats
(7)
$11.97
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Senergy (selamectin) Topical for Cats 15.1 - 22 lbs, 3 doses
(0)
$50.59
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Senergy (selamectin) Topical for Kittens and Puppies Up to 5 lbs, 3 doses
(0)
$42.83
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Bravecto Plus Topical Solution for Cats, 13.8-27.5 lb (Purple), 1 Dose,  2-Month Supply
(0)
$55.99
5X points (10% back in savings) on ALL cat products
Sign In & Enjoy Free Shipping Over $49
Bravecto Plus Topical Solution for Cats, 2.6-6.2 lb (Green), 1 Dose, 2-Month Supply
(2)
$54.99
5X points (10% back in savings) on ALL cat products
Sign In & Enjoy Free Shipping Over $49
Selarid (selamectin) Topical for Cats 15.1-22 lbs, Taupe (6 Month Supply)
(0)
$73.49
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Selarid (selamectin) Topical for Kittens/Puppies Up to 5 lbs, Mauve (3 Month Supply)
(0)
$32.49
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Advantage Multi Cat 5-in-1 Heartworm Prevention - Kills Fleas - Cats 5.1-9 lbs. - 6-Month Supply
2 sizes
(2)
$19.78 - $128.59
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Revolution Topical for Cats 15.1-22 lbs Taupe
3 sizes
(1)
$124.00 - $427.08
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Revolution Plus for Cats 2.8-5.5 lbs Gold - 3 or 6 Month Supply
2 sizes
(0)
$75.18 - $145.25
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Bravecto Topical Solution for Cats, 13.8 - 27.5 lbs 500 mg Purple
(1)
$77.99
5X points (10% back in savings) on ALL cat products
Sign In & Enjoy Free Shipping Over $49
Bravecto Topical Solution for Cats, 2.6 - 6.2 lbs 112.5 mg Green
(0)
$75.99
5X points (10% back in savings) on ALL cat products
Sign In & Enjoy Free Shipping Over $49
Advantage Multi for Cats 2-5 lbs (Turquoise), Flea Treatment & Heartworm Prevention, 3 Month Supply
(1)
$80.49
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Revolution Topical for Puppies and Kittens up to 5 lbs Pink - 3 Month Supply
(0)
$76.30
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Sergeant's Guardian Flea and Tick Topical for Cats - 6lbs and over - 3 Month Supply
(8)
$5.99
$9.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
5X points (10% back in savings) on ALL cat products
+ 1 more
Only Natural Pet® EasyDefense™ Flea & Tick Spray
(153)
$11.99
Buy 1, get the 2nd 25% OFF off dog and cat Flea & Tick products including prescriptions
Free Same-Day Delivery, No Order Minimum!
+ 1 more
  1. 1
Fleas and ticks are absolutely no fun for you or your pet cat. They can cause issues for your pet when not addressed. If your cat has fleas or ticks, you should talk to your vet about the best options to help get rid of them. Pet parents can find a great selection of cat flea topical drops and cat flea spot-ons at PetSmart. We want to help you protect your cat from fleas and ticks. 
Our selection of cat flea/tick prevention products extends far past only flea and tick topical drops for cats. We also carry: 
You are sure to find what you need to help get rid of fleas or protect your cats from them at PetSmart. Need other cat supplies while you’re here? We have you covered. 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.