Spot On

(35 results)
Advantage® II Over 9 lbs Cat Flea Prevention & Treatment
4 sizes
(715)
$19.99 - $68.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Frontline Plus Cat Flea & Tick Treatment
3 sizes
(558)
$39.99 - $96.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Advantage® II 5-9 lbs Cat Flea Prevention & Treatment
4 sizes
(398)
$19.99 - $69.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Advantage Topical Cat Flea Treatment and Prevention For Large Cats Over 9 lbs.
(291)
$14.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(192)
$14.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Revolution Plus for Cats 5.6-11 lbs Orange - 3 or 6 Month Supply
2 sizes
(14)
$91.74 - $165.24
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Revolution Plus for Cats 11.1-22 lbs Green - 3 or 6 Month Supply
2 sizes
(19)
$97.38 - $170.34
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Cheristin, Cat Flea and Tick Treatment and Prevention
3 sizes
(1)
$17.99 - $84.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Advantage® XD Over 9 lbs Large Cat Flea Prevention & Treatment
3 sizes
(748)
$37.99 - $99.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
NextStar® Flea & Tick Prevention for Cats
2 sizes
(177)
$34.99 - $52.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
PetArmor® Plus for Cats Over 1.5 lbs Flea & Tick Spot On Treatment
2 sizes
(1020)
$26.14 - $42.49
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Bravecto Topical Solution for Cats, 6.2 - 13.8 lbs 250 mg Blue
(5)
$72.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Sign In & Enjoy Free Shipping Over $49
Advantage Multi for Cats 9.1-18 lbs
2 sizes
(1)
$19.99 - $129.79
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Advantage® II 2-5 lbs Kitten Flea Prevention & Treatment
(58)
$33.59
$34.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Advantage® XD 1.8-9 lbs Small Cat Flea Prevention & Treatment
3 sizes
(613)
$37.99 - $99.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Bravecto Plus Topical Solution for Cats
(1)
$51.99 - $52.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Cats 5.1-15 lbs Blue
3 sizes
(2)
$114.97 - $416.22
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Selarid (selamectin) Topical for Cats 5.1-15 lbs, Blue (6 Month Supply)
(0)
$71.99
$92.59
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Only Natural Pet Flea & Tick Spot On 3 count
(149)
$19.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
+ 3 more
Liquid-Vet® Feline Flea & Tick+Support Formula
(0)
$11.49
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Vetality Naturals Flea & Tick Topicals for Cats
(7)
$12.89
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Senergy (selamectin) Topical for Cats 15.1 - 22 lbs, 3 doses
(0)
$52.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Senergy (selamectin) Topical for Cats 5.1 - 15 lbs, 3 doses
(1)
$49.39
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Senergy (selamectin) Topical for Kittens and Puppies Up to 5 lbs, 3 doses
(0)
$42.89
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Selarid (selamectin) Topical for Cats 15.1-22 lbs, Taupe (6 Month Supply)
(0)
$73.49
$94.79
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Selarid (selamectin) Topical for Kittens/Puppies Up to 5 lbs, Mauve (3 Month Supply)
(0)
$32.49
$43.59
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Advantage Multi for Cats 5.1-9 lbs
2 sizes
(2)
$19.79 - $128.59
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Revolution Topical for Cats 15.1-22 lbs Taupe
3 sizes
(1)
$124.00 - $427.08
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Revolution Plus for Cats 2.8-5.5 lbs Gold - 3 or 6 Month Supply
2 sizes
(0)
$75.18 - $145.25
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Bravecto Topical Solution for Cats, 13.8 - 27.5 lbs 500 mg Purple
(1)
$73.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Sign In & Enjoy Free Shipping Over $49
Bravecto Topical Solution for Cats, 2.6 - 6.2 lbs 112.5 mg Green
(0)
$71.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Sign In & Enjoy Free Shipping Over $49
Advantage Multi for Cats 2-5 lbs, 3 Month Supply
(1)
$80.49
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Revolution Topical for Puppies and Kittens up to 5 lbs Pink - 3 Month Supply
(0)
$76.30
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Sergeant's Guardian Flea and Tick Topical for Cats - 6lbs and over - 3 Month Supply
(6)
$5.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
Save 35% On Your First Autoship Order!
+ 1 more
Only Natural Pet® Cat Flea, Tick & Mosquito Treatment
(306)
$19.99
Members earn 2X, 3X or 4X points on ALL purchases thru 2/1*
  1. 1
Fleas and ticks are absolutely no fun for you or your pet cat. They can cause issues for your pet when not addressed. If your cat has fleas or ticks, you should talk to your vet about the best options to help get rid of them. Pet parents can find a great selection of cat flea topical drops and cat flea spot-ons at PetSmart. We want to help you protect your cat from fleas and ticks. 
Our selection of cat flea/tick prevention products extends far past only flea and tick topical drops for cats. We also carry: 
You are sure to find what you need to help get rid of fleas or protect your cats from them at PetSmart. Need other cat supplies while you’re here? We have you covered. 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.