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(35 results)
Advantage® II Over 9 lbs Cat Flea Prevention & Treatment
4 sizes
(709)
$16.99 - $68.99
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Frontline Plus Cat Flea & Tick Treatment
3 sizes
(554)
$39.99 - $96.99
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Advantage® II 5-9 lbs Cat Flea Prevention & Treatment
4 sizes
(396)
$16.99 - $68.99
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Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(192)
$14.99
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Advantage Topical Cat Flea Treatment and Prevention For Large Cats Over 9 lbs.
(291)
$14.99
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Revolution Plus for Cats 11.1-22 lbs Green - 3 or 6 Month Supply
2 sizes
(19)
$91.09 - $159.29
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Revolution Plus for Cats 5.6-11 lbs Orange - 3 or 6 Month Supply
2 sizes
(14)
$85.71 - $154.49
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Cheristin, Cat Flea and Tick Treatment and Prevention
3 sizes
(1)
$16.69 - $78.69
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Advantage® II 2-5 lbs Kitten Flea Prevention & Treatment
(58)
$33.59
$34.99
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Advantage® XD Over 9 lbs Large Cat Flea Prevention & Treatment
3 sizes
(746)
$34.99 - $95.99
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PetArmor® Plus for Cats Over 1.5 lbs Flea & Tick Spot On Treatment
2 sizes
(1016)
$26.14 - $42.49
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NextStar® Flea & Tick Prevention for Cats
2 sizes
(176)
$34.99 - $52.99
Free Same-Day Delivery, No Order Minimum!
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Advantage® XD 1.8-9 lbs Small Cat Flea Prevention & Treatment
3 sizes
(613)
$34.99 - $95.99
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Advantage Multi for Cats 9.1-18 lbs
2 sizes
(1)
$19.99 - $119.99
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Revolution Topical for Cats 5.1-15 lbs Blue
3 sizes
(2)
$104.49 - $378.99
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Bravecto Plus Topical Solution for Cats
(1)
$51.99 - $52.99
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Selarid (selamectin) Topical for Cats 5.1-15 lbs, Blue (6 Month Supply)
(0)
$71.99
$92.59
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Bravecto Topical Solution for Cats, 6.2 - 13.8 lbs 250 mg Blue
(5)
$72.99
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Senergy (selamectin) Topical for Cats 5.1 - 15 lbs, 3 doses
(1)
$49.39
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Only Natural Pet Flea & Tick Spot On 3 count
(147)
$19.99
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Liquid-Vet® Feline Flea & Tick+Support Formula
(0)
$11.49
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Vetality Naturals Flea & Tick Topicals for Cats
(7)
$12.89
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Senergy (selamectin) Topical for Cats 15.1 - 22 lbs, 3 doses
(0)
$52.99
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Selarid (selamectin) Topical for Cats 15.1-22 lbs, Taupe (6 Month Supply)
(0)
$73.49
$94.79
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Advantage Multi for Cats 5.1-9 lbs
2 sizes
(2)
$19.79 - $118.69
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Revolution Topical for Cats 15.1-22 lbs Taupe
3 sizes
(1)
$112.79 - $388.99
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Revolution Plus for Cats 2.8-5.5 lbs Gold - 3 or 6 Month Supply
2 sizes
(0)
$70.29 - $135.79
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Bravecto Topical Solution for Cats, 13.8 - 27.5 lbs 500 mg Purple
(1)
$73.99
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Bravecto Topical Solution for Cats, 2.6 - 6.2 lbs 112.5 mg Green
(0)
$71.99
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Advantage Multi for Cats 2-5 lbs, 3 Month Supply
(1)
$74.29
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Only Natural Pet® Cat Flea, Tick & Mosquito Treatment
(306)
$19.99
Save 35% On Your First Autoship Order!
  1. 1
Fleas and ticks are absolutely no fun for you or your pet cat. They can cause issues for your pet when not addressed. If your cat has fleas or ticks, you should talk to your vet about the best options to help get rid of them. Pet parents can find a great selection of cat flea topical drops and cat flea spot-ons at PetSmart. We want to help you protect your cat from fleas and ticks. 
Our selection of cat flea/tick prevention products extends far past only flea and tick topical drops for cats. We also carry: 
You are sure to find what you need to help get rid of fleas or protect your cats from them at PetSmart. Need other cat supplies while you’re here? We have you covered. 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.