Spot On

(35 results)
Advantage® II Over 9 lbs Cat Flea Prevention & Treatment
4 sizes
(679)
$16.99 - $70.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Frontline Plus Cat Flea & Tick Treatment
3 sizes
(536)
$39.99 - $98.99
Save 40% on your first Autoship Order of Frontline
2X points (4% back in savings) on flea and tick purchases
+ 2 more
Advantage® II 5-9 lbs Cat Flea Prevention & Treatment
4 sizes
(379)
$16.99 - $70.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(1)
$14.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Revolution Plus for Cats 11.1-22 lbs Green - 3 or 6 Month Supply
2 sizes
(17)
$91.09 - $159.29
Sign In & Enjoy Free Shipping Over $49
Revolution Plus for Cats 5.6-11 lbs Orange - 3 or 6 Month Supply
2 sizes
(13)
$85.79 - $154.49
Sign In & Enjoy Free Shipping Over $49
Advantage® II 2-5 lbs Kitten Flea Prevention & Treatment
(54)
$33.59
$34.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Advantage® XD Over 9 lbs Large Cat Flea Prevention & Treatment
3 sizes
(744)
$35.99 - $98.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
PetArmor® Plus for Cats Over 1.5 lbs Flea & Tick Spot On Treatment
2 sizes
(991)
$24.99 - $39.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Cheristin, Cat Flea and Tick Treatment and Prevention
3 sizes
(0)
$17.99 - $78.69
2X points (4% back in savings) on flea and tick purchases
NextStar® Flea & Tick Prevention for Cats
2 sizes
(169)
$35.99 - $52.99
10X points (20% back in savings) on NextStar & CapStar flea & tick products
2X points (4% back in savings) on flea and tick purchases
Advantage® XD 1.8-9 lbs Small Cat Flea Prevention & Treatment
3 sizes
(611)
$35.99 - $98.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Advantage Topical Cat Flea Treatment and Prevention For Large Cats Over 9 lbs.
(1)
$14.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Bravecto Topical Solution for Cats, 6.2 - 13.8 lbs 250 mg Blue
(5)
$72.99
Sign In & Enjoy Free Shipping Over $49
Advantage Multi for Cats 9.1-18 lbs
2 sizes
(1)
$19.99 - $119.80
Sign In & Enjoy Free Shipping Over $49
Bravecto Plus Topical Solution for Cats
(1)
$51.99 - $52.99
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Cats 5.1-15 lbs Blue
3 sizes
(1)
$104.49 - $378.99
Sign In & Enjoy Free Shipping Over $49
Only Natural Pet® Cat Flea, Tick & Mosquito Treatment
(442)
$19.99
2X points (4% back in savings) on flea and tick purchases
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Selarid (selamectin) Topical for Cats 5.1-15 lbs, Blue (6 Month Supply)
(0)
$71.99
$92.59
Sign In & Enjoy Free Shipping Over $49
Bravecto Topical Solution for Cats, 13.8 - 27.5 lbs 500 mg Purple
(1)
$73.99
Sign In & Enjoy Free Shipping Over $49
Only Natural Pet Flea & Tick Spot On 3 count
(0)
$19.99
2X points (4% back in savings) on flea and tick purchases
Liquid-Vet® Feline Flea & Tick+Support Formula
(0)
$11.49
2X points (4% back in savings) on flea and tick purchases
Sign In & Enjoy Free Shipping Over $49
Vetality Naturals Flea & Tick Topicals for Cats
(7)
$12.89
2X points (4% back in savings) on flea and tick purchases
Sign In & Enjoy Free Shipping Over $49
Senergy (selamectin) Topical for Cats 15.1 - 22 lbs, 3 doses
(0)
$50.59
Sign In & Enjoy Free Shipping Over $49
Senergy (selamectin) Topical for Cats 5.1 - 15 lbs, 3 doses
(1)
$49.39
Sign In & Enjoy Free Shipping Over $49
Selarid (selamectin) Topical for Cats 15.1-22 lbs, Taupe (6 Month Supply)
(0)
$73.49
$94.79
Sign In & Enjoy Free Shipping Over $49
Advantage Multi for Cats 5.1-9 lbs
2 sizes
(2)
$19.79 - $118.69
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Cats 15.1-22 lbs Taupe
3 sizes
(1)
$112.79 - $388.99
Sign In & Enjoy Free Shipping Over $49
Revolution Topical for Puppies and Kittens up to 5 lbs Pink
(0)
$71.99
Sign In & Enjoy Free Shipping Over $49
Bravecto Topical Solution for Cats, 2.6 - 6.2 lbs 112.5 mg Green
(0)
$71.99
Sign In & Enjoy Free Shipping Over $49
Advantage Multi for Cats 2-5 lbs, 3 Month Supply
(0)
$74.29
Sign In & Enjoy Free Shipping Over $49
Sergeant's Guardian Flea and Tick Topical for Cats - 6lbs and over - 3 Month Supply
(4)
$5.99
$9.99
2X points (4% back in savings) on flea and tick purchases
Sign In & Enjoy Free Shipping Over $49
  1. 1
Fleas and ticks are absolutely no fun for you or your pet cat. They can cause issues for your pet when not addressed. If your cat has fleas or ticks, you should talk to your vet about the best options to help get rid of them. Pet parents can find a great selection of cat flea topical drops and cat flea spot-ons at PetSmart. We want to help you protect your cat from fleas and ticks. 
Our selection of cat flea/tick prevention products extends far past only flea and tick topical drops for cats. We also carry: 
You are sure to find what you need to help get rid of fleas or protect your cats from them at PetSmart. Need other cat supplies while you’re here? We have you covered. 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.