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Get flea & tick preventions, treatments & tips for your kitty

Flea & Tick

(23 results)
Advantage® II Over 9 lbs Cat Flea Prevention & Treatment
4 sizes
(697)
$16.99 - $68.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® II 5-9 lbs Cat Flea Prevention & Treatment
4 sizes
(392)
$16.99 - $68.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® II 2-5 lbs Kitten Flea Prevention & Treatment
(56)
$33.59
$34.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage Topical Cat Flea Treatment and Prevention For Large Cats Over 9 lbs.
(288)
$14.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(192)
$14.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® II Over 55 lbs Dog Flea & Lice Treatment
2 sizes
(71)
$50.99 - $66.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage Multi for Cats 9.1-18 lbs
2 sizes
(1)
$19.99 - $119.99
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
Advantage Multi Topical for Dogs 20.1-55 lbs Red
2 sizes
(1)
$21.69 - $134.99
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
Advantage Multi Topical for Dogs 9.1-20 lbs Teal
2 sizes
(5)
$21.49 - $134.99
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
Advantage® II 21-55 lbs Dog Flea & Lice Treatment
2 sizes
(60)
$50.99 - $66.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage Multi Topical for Dogs 55.1-88 lbs Blue
2 sizes
(1)
$21.79 - $134.99
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
Advantage® Flea & Tick Kitten and Cat Shampoo
(32)
$14.49
$16.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® Flea & Tick Dog Treatment Spray
2 sizes
(68)
$14.49 - $19.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® II 11-20 lbs Dog Flea & Lice Treatment
2 sizes
(57)
$50.99 - $66.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® II 3-10 lbs Dog Flea & Lice Treatment
2 sizes
(72)
$50.99 - $66.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage Multi Topical for Dogs 88.1-110 lbs Brown
2 sizes
(5)
$21.89 - $134.99
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
Advantage Multi Topical for Dogs 3-9 lbs Green
2 sizes
(5)
$21.39 - $134.99
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
Advantage Dog Flea and Tick Spray - 24 Fl Oz
(1)
$20.99
$28.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® Flea & Tick Cat Spray
(91)
$14.49
$16.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® Carpet & Upholstery Spray
(22)
$20.98
$26.99
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage® Flea & Tick Dog & Puppy Shampoo
3 sizes
(78)
$14.49 - $26.49
Buy 1, Get the 2nd 25% off ALL Flea & Tick
Save 35% On Your First Autoship Order!
+ 2 more
Advantage Multi for Cats 5.1-9 lbs
2 sizes
(2)
$19.79 - $118.69
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
Advantage Multi for Cats 2-5 lbs, 3 Month Supply
(0)
$74.29
Save 40% on your 1st Pharmacy Autoship Order
Stack and save an additional 35% on your 1st Pharmacy Autoship order with code SAVE35RX
+ 1 more
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Is it peak flea and tick season? If so, it’s time to protect your cat or kitten from those pesky pests. Pet parents everywhere can agree that fleas and ticks are not welcome on your cat or in your home. PetSmart carries cat flea control and tick removal solutions to help protect your feline friends (and your home) from fleas and ticks. At PetSmart, you’ll find cat flea treatments that are specially designed for your cat and offer protection from pests indoors and out when used as directed. 
Check out our wide selection of flea and tick treatment options that work best for your cat. From conventional collars and sprays to cat flea pills and topical treatments, we carry the latest and most effective pest control products for cats and kittens at PetSmart. Getting rid of fleas and other pests requires breaking their life cycle, which means killing both the eggs and larvae in addition to the adults that are more easily seen. With combs and removal tools, shampoos and dips, cat flea medications and household pest sprays, you can help protect your cat from a wide range of flea-borne and tick-borne illnesses.
At PetSmart, we carry flea and tick solutions so you can help protect your pets from those pesky pests, and get rid of them when they do present a problem. Browse our flea and tick products, such as:
Not looking for cat flea treatment and tick removal products? PetSmart makes it easy to stock up on all your feline friend’s favorites. Shop some of our other cat supplies, like wet cat foodlittercat beds, and more. 
PetSmart also offers convenient shopping with curbside or in-store pickup. Need something today? We have select items available for same-day delivery in most areas powered by DoorDash. For items you purchase frequently, PetSmart has Autoship that automatically delivers the items you want to your door as often as you’d like. Check the website to see which items are eligible.