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Get flea & tick preventions, treatments & tips for your dog

Flea & Tick

(172 results)
Seresto® Flea & Tick Dog Collar - Large
2 sizes
(1799)
$59.99 - $107.99
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Seresto® Flea & Tick Dog Collar - Small
2 sizes
(147)
$59.99 - $107.99
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K9 Advantix® II 21-55 lbs Dog Flea & Tick Treatment
4 sizes
(275)
$18.99 - $79.99
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Capstar™ Over 25 lbs Dog Flea Treatment
2 sizes
(498)
$43.49 - $71.99
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Vet's Best® Flea + Tick Home Spray
(134)
$15.48
$17.99
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PetArmor® Home Flea & Tick Home & Carpet Spray
(590)
$8.79
$10.99
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Simparica Trio Chewable Tablets for Dogs - 44.1-88 lbs, Green Box
2 sizes
(44)
$42.19 - $214.99
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Simparica Trio Chewable Tablets for Dogs - 22.1-44 lbs, Blue Box
2 sizes
(19)
$41.09 - $214.99
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Simparica Trio Chewable Tablets for Dogs - 11.1-22 lbs, Caramel Box
(16)
$188.98
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Frontline Plus Flea & Tick Dog Treatment 5-22 lbs
3 sizes
(560)
$39.99 - $96.99
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Capstar™ 2-25 Lb Dog Flea Treatment
2 sizes
(803)
$43.19 - $72.99
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Frontline Plus Flea & Tick Dog Treatment 45-88 lbs
3 sizes
(620)
$39.99 - $96.99
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K9 Advantix® II Over 55 lbs Dog Flea & Tick Treatment
4 sizes
(314)
$18.99 - $79.99
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Frontline Plus Flea and Tick Dog Treatment 23-44 lbs
3 sizes
(369)
$39.99 - $96.99
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Advantage Topical Cat Flea Treatment and Prevention For Small Cats 2-9 lbs.
(192)
$14.99
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K9 Advantix® II 11-20 lbs Dog Flea & Tick Treatment
4 sizes
(274)
$18.99 - $79.99
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PetArmor® Home Flea & Tick Carpet Powder
(447)
$8.99
$11.99
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Only Natural Pet® EasyDefense™ All-in-One Flea Remedy Powder
(595)
$14.99
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K9 Advantix® Classic 55+ lbs Dog Flea & Tick Treatment
(145)
$14.99
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K9 Advantix® Classic 21-55 lbs Dog Flea & Tick Treatment
(200)
$14.99
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PetArmor® Flea & Tick Oatmeal Shampoo for Dogs - Hawaiian Ginger - 18 Fl
(515)
$7.19
$10.99
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PetArmor® Flea & Tick Shampoo for Dogs - Sunwashed Linen
(498)
$6.99
$10.99
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Top Paw® Flea Pet Comb
(97)
$2.99
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NexGard Chewable Tablets for Dogs 24.1 - 60.0 lbs
3 sizes
(8)
$34.99 - $158.39
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NexGard Chewable Tablets for Dogs 60.1-121 lbs
3 sizes
(20)
$34.99 - $159.99
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NexGard Chewable Tablets for Dogs 10.1-24 lbs
3 sizes
(12)
$34.99 - $155.09
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Simparica Trio Chewable Tablets for Dogs - 88.1-132 lbs, Brown Box
2 sizes
(5)
$42.69 - $214.99
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Simparica Trio Chewable Tablets for Dogs - 5.6-11 lbs, Purple Box
2 sizes
(6)
$37.29 - $188.98
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Bravecto Chews 44-88 lbs Blue, 1000 mg 1 chewable, 12 weeks acting
(8)
$80.99
$82.99
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Advantus™ Dog Flea Treatment - 23-110 Lbs
2 sizes
(140)
$32.19 - $67.29
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Bravecto Chews 9.9-22 lbs Orange, 250 mg 1 chewable, 12 weeks acting
(8)
$76.99
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Simparica Chewable Tablets for Dogs 44-88 lbs Green - 3 or 6 Month Supply
2 sizes
(7)
$74.79 - $134.99
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Credelio Flea & Tick Chewable Tablets for Dogs & Puppies 50.1-100 lbs (900 mg) Blue
3 sizes
(4)
$29.99 - $149.68
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PetArmor® Plus Flea & Tick Collar for Dogs - 2 Count
(760)
$34.99
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Frontline Plus Flea & Tick Dog Treatment 89-132 lbs
3 sizes
(512)
$39.99 - $96.99
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Trifexis Chewable Tablets for Dogs 60.1-120 lbs Brown
2 sizes
(5)
$26.99 - $164.99
Sepnd $100 on select Pharmacy, Save $20 on your Order!
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Bravecto Chews 22-44 lbs Green, 500 mg 1 chewable, 12 weeks acting
(4)
$79.99
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Trifexis Chewable Tablets for Dogs 10.1-20 lbs Orange
2 sizes
(5)
$24.50 - $146.99
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Wondercide Flea & Tick Shampoo For Dogs & Cats
(217)
$19.99
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Wondercide Lemongrass Scent Home & Pet Flea & Tick Spray
2 sizes
(3753)
$13.99 - $26.99
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Dog Flea Treatment Options at PetSmart 

Fleas are a common nuisance for dogs, leading to discomfort and potential health issues. At PetSmart, you can find a wide range of dog flea treatments to effectively address flea infestations and keep your furry friend comfortable. From Capstar for dogs providing immediate relief to long-term solutions like Frontline Plus and K9 Advantix II, our assortment ensures you have access to the best options to tackle fleas. 

Effective Flea Treatments for Dogs 

Choosing the right flea treatment for your dog depends on several factors, including the severity of the infestation and your pet’s lifestyle. Here are some of the top choices available at PetSmart: 
  • Capstar Flea Tablets: Known for providing fast relief by killing fleas on dogs within hours. Ideal for quick, temporary infestation control. 
  • Frontline Plus: Offers long-lasting protection against fleas and ticks, killing adults, eggs, and larvae, preventing future infestations. 
  • K9 Advantix II: A topical treatment that repels and kills fleas, ticks, and mosquitoes, providing comprehensive protection for your pet. 
  • NexGard Chewables: An oral flea and tick treatment that protects against further infestations with a tasty, beef-flavored chew. 
  • Flea Shampoo for Dogs: Designed to wash away fleas, dirt, and debris, while soothing irritated skin, an essential part of your dog's grooming routine. 
  • Flea Spray: Used to treat both your dog and their living environment, offering flexible flea control. 
Keep your pet protected year-round with Autoship from PetSmart, saving time and money on regular deliveries of your flea prevention products. Visit our website to explore our full range of dog flea treatments and find the solution that works best for you and your dog. 

Frequently Asked Questions (FAQs) 

What is the most effective treatment for dog fleas? 

The effectiveness of a treatment can vary by your dog's needs. Products like Frontline Plus and K9 Advantix II are popular for their long-lasting protection, while Capstar provides immediate relief. 

What kills fleas on dogs immediately? 

Capstar is renowned for its ability to kill fleas on dogs quickly, within hours of administration, making it ideal for immediate relief from flea infestations. 

What is the best flea treatment for dogs? 

The best flea treatment depends on your dog's specific needs and lifestyle. Top-rated options include Frontline Plus for comprehensive protection, and NexGard Chewables for an easy-to-administer oral option. 

Do you need to treat your house if your dog has fleas? 

Yes, treating your home is important to prevent reinfestation. Using flea sprays for carpets and furniture can help eliminate fleas from your living space.