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Flea & Tick

(85 results)
Seresto® Vet-Recommended 8-Month Collar, Flea & Tick Prevention for Cats
2 sizes
(1041)
$59.99 - $115.99
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Advantage® II Flea Prevention & Treatment for Large Cats over 9 lbs, Monthly Doses
3 sizes
(895)
$33.59 - $69.99
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Capstar™ Fast-Acting Oral Flea Treatment for Cats 2-25 lbs
2 sizes
(677)
$43.19 - $70.19
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Frontline Plus Flea & Tick Spot Treatment for Cats, 1.5 lbs and over
3 sizes
(578)
$37.12 - $98.98
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Advantage® II Flea Prevention & Treatment for Small Cats 5-9 lbs, Monthly Doses
4 sizes
(495)
$19.99 - $69.99
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PetArmor® Plus Flea & Tick Prevention for Cats over 1.5 lbs, Spot On Treatment
2 sizes
(1024)
$26.14 - $39.99
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Advantage Topical Flea Treatment and Prevention for Large Cats Over 9 lbs, 2 monthly doses
(298)
$14.99
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PetArmor® CapAction Fast-Acting Oral Flea Treatment for Cats 2-25 lbs, 6 doses
(56)
$31.49
$34.99
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PetArmor® Home Flea & Tick Home & Carpet Spray, 16 oz
(602)
$11.99
$13.99
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K9 Advantix® Flea, Tick & Mosquito Prevention for Extra Large Dogs 55+ lbs, Monthly Dose Treatment
(148)
$14.99
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Wondercide Natural Home and Pet Flea & Tick Spray for Dogs and Cats, Lemongrass Scent, 16oz
(1755)
$26.99
$27.99
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Advantage Topical Flea Treatment and Prevention for Small Cats 2-9 lbs, 2 monthly doses
(200)
$14.99
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
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Whisker City® Pet Flea Comb
(132)
$4.62
$8.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Free Same-Day Delivery, No Order Minimum!
+ 1 more
Flys-Off® Insect Repellent for Dogs & Cats, 6oz
(56)
$10.59
$13.99
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
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Revolution Plus for Cats 5.6-11 lbs Orange - 3 or 6 Month Supply
2 sizes
(16)
$91.74 - $165.24
Save $20 when you spend $100+ on prescriptions thru 7/5
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Revolution Plus for Cats 11.1-22 lbs Green - 3 or 6 Month Supply
2 sizes
(21)
$97.38 - $170.34
Save $20 when you spend $100+ on prescriptions thru 7/5
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Cheristin, Cat Flea and Tick Treatment and Prevention
3 sizes
(43)
$17.99 - $84.99
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Save 35% On Your First Autoship Order!
+ 1 more
PetArmor® Extend Flea & Tick Treatment & Prevention Collar for Cats, 8 Months of Protection
(363)
$44.99
$47.99
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Advantage® XD Flea Prevention & Treatment for Large Cats over 9 lbs, 2 Months Protection per Dose
3 sizes
(754)
$37.99 - $99.99
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Advantage® II Flea Prevention & Treatment for Cats and Kittens 2-5 lbs, Monthly Doses
(58)
$33.59
$34.99
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NextStar® Flea & Tick Waterproof Topical Prevention for Cats over 3.5 lbs
2 sizes
(181)
$34.99 - $52.99
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NexGard COMBO Topical Solution for Cats 5.6-16.5 lbs (Yellow Box) - 1,3, or 6 Doses
3 sizes
(5)
$38.69 - $184.99
Save $20 when you spend $100+ on prescriptions thru 7/5
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
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Wondercide Natural Home and Pet Flea & Tick Spray for Dogs and Cats, Cedarwood Scent, 16oz
(1515)
$26.99
$27.99
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Wondercide Natural Home and Pet Flea & Tick Spray for Dogs, Peppermint Scent, 16oz
(1444)
$26.99
$27.99
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Credelio CAT Flea & Tick Prevention & Treatment for Cats 4.1 - 17 lbs - 1, 3, or 6 Month Supply
3 sizes
(2)
$25.55 - $138.31
Save $20 when you spend $100+ on prescriptions thru 7/5
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
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Only Natural Pet® EasyDefense™ Flea &Tick Collar for Cats, Protects up to 3 Months
(131)
$14.99
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
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Vet's Best® Natural Flea & Tick Dog and Home Spray, Peppermint Scent, 32oz
(138)
$15.48
$17.99
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Only Natural Pet® EasyDefense™ All-in-One Flea Remedy Powder, 8oz
(614)
$14.99
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
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Advantage® XD Flea Prevention & Treatment for Small Cats 1.8-9 lbs, 2 Months Protection per Dose
3 sizes
(617)
$37.99 - $99.99
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Bravecto Topical Solution for Cats, 6.2 - 13.8 lbs 250 mg Blue
(5)
$76.99
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Advantage Multi Topical Solution for Cats, 9.1-18 lbs, 1 or 6 Month Supply
2 sizes
(1)
$19.97 - $129.79
Save $20 when you spend $100+ on prescriptions thru 7/5
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Vet's Best® Flea & Tick Cat & Home Spray - Plant Based Ingredients - Cotton Spice Scent -32 FL OZ
(2)
$15.48
$19.99
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PetArmor® Flea & Tick Cat Shampoo, Coconut Berry scent, 12 oz
(32)
$8.99
$11.99
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Wondercide Natural Flea & Tick Shampoo for Dogs and Cats, Kills and Repels, Cedarwood Scent, 12 oz
(9)
$19.99
$21.99
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Only Natural Pet® EasyDefense™ Flea &Tick Squeeze-On Treatment for Cats, 3 count
(155)
$19.99
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Wondercide Natural Flea & Tick Shampoo for Dogs, Peppermint Scent, 12oz
(261)
$19.99
$21.99
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Bravecto Plus Topical Solution for Cats, 6.2-13.8 lb (Blue), 1 Dose,  2-Month Supply
(0)
$56.99
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Selarid (selamectin) Topical for Cats 5.1-15 lbs, Blue (6 Month Supply)
(0)
$71.91
Save $20 when you spend $100+ on prescriptions thru 7/5
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
+ 2 more
Revolution Topical for Cats 5.1-15 lbs Blue
3 sizes
(2)
$114.97 - $419.99
Save $20 when you spend $100+ on prescriptions thru 7/5
10X points (20% back in savings) on ALL flea & tick products including prescriptions.
+ 2 more
Only Natural Pet® EasyDefense™ Flea & Tick Home Spray, 32oz
(170)
$11.29
$18.99
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Comprehensive Cat Flea Treatment Solutions at PetSmart

Flea infestations can be a nuisance for both cats and their owners, but effective flea treatment solutions are available to help protect your feline friends. At PetSmart, we offer a full range of cat flea treatment options, including flea medicine for cats, flea shampoos, flea sprays, and vet-recommended solutions like Advantage II for cats. These treatments are designed to eliminate fleas quickly and efficiently, ensuring both your pet's comfort and your home's safety.

Help Your Cat Get Relief Fast and Stop Fleas from Spreading

If your cat has fleas, it’s important to act quickly. Fleas don’t just make your cat itchy, they can spread fast, lay eggs in your home, and become a bigger problem over time. Catching and treating an outbreak early helps keep your cat comfortable and your home protected.
One fast option many pet parents use is an oral flea tablet. These tablets start working within 30 minutes to kill adult fleas and give your cat quick relief. They're a great way to stop the problem right away before switching to a longer-lasting treatment.
After that, you can use other products like monthly topical treatments, flea collars, or sprays to keep fleas from coming back. No matter which option you choose, treating your cat and home right away is the best way to stop fleas before they get worse.

Types of Flea Treatment Options

  • Flea Shampoo for Cats: Cleanse and protect your pet's coat with specially formulated shampoos that target fleas and larvae.
  • Flea Spray for Cats: Convenient for on-the-go protection, sprays help guard your pet and indoor areas against fleas and ticks.
  • Flea Powder for Cats: Easy-to-use powders that offer a dust-free treatment experience for your pet's skin and fur.
  • Vet-Recommended Flea Treatments: Trust in vet recommended flea treatments for cats for reliable and effective protection.
  • Advantage II for Cats: A long-lasting topical treatment that offers monthly protection by killing fleas through contact.
Browse PetSmart's selection of flea and tick treatments for cats and keep your pet safe from pests all year round. Look for options that suit your cat's lifestyle, and enjoy the convenience of curbside pickup, Autoship, or same-day delivery to get started on protecting your pet today.

Frequently Asked Questions (FAQs)

What is the most effective flea treatment for cats?

The most effective flea treatments often include options like Advantage II or Frontline, which are topicals applied monthly to prevent and kill fleas on cats.

What is the fastest way to kill cat fleas?

For quick action, Capstar tablets can be administered, which begin to kill adult fleas within 30 minutes, offering fast relief from active infestations.

What to do if an indoor cat has fleas?

Treat your cat with a proven flea treatment such as Advantage II or Frontline. Thoroughly clean your home environment to eliminate lingering fleas, focusing on fabric surfaces, carpets, and pet bedding.

What is the best flea treatment for cats without a vet prescription?

Over-the-counter options such as Advantage II and Frontline Plus are available without a prescription and effectively manage flea infestations.