Numelvi (atinvicitinib) Tablets for Dogs - 4.8mg, 7.2mg, 21.6mg, 31.6mg - 30 or 90 Tablets

• Acts fast: Absorbed quickly to start relieving allergic itch within 2-4 hours.1*


• Suitable for young dogs: Labeled for use in dogs and puppies 6 months of age and older.


• Easy, once daily dosing: Given once daily with food at or around mealtime.


• No interference with routine treatments: Can be used with other routine treatments and vaccines.
  


• 2†NUMELVI™ (atinvicitinib) tablets is a prescription medication for the control of itch associated with allergic dermatitis in dogs.
  


• Numelvi starts working in as little as 2 to 4 hours1* to relieve itch and deliver the comfort your dog deserves.
  


• Numelvi is given once daily with food at or around mealtime and is labeled for use in dogs and puppies 6 months of age and older.


• Discover NUMELVI™ (atinvicitinib) tablets for dogs. Available by prescription only.


• IMPORTANT SAFETY INFORMATION:NUMELVI is not for use in dogs less than 6 months of age or those with serious infections.
  


• NUMELVI may increase susceptibility to opportunistic infections, including demodicosis and interdigital furunculosis.
  


• Consider the risks and benefits of treatment prior to initiating NUMELVI in dogs with a history of recurrent demodicosis.
  


• NUMELVI is a JAK inhibitor. New neoplastic conditions (benign and malignant) have been reported in dogs treated with other JAK inhibitors.
  


• The effectiveness and safety of NUMELVI have not been evaluated in a field study beyond 28 days.
  


• The safe use of NUMELVI has not been evaluated in breeding, pregnant, or lactating dogs, nor in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents. For complete safety information, refer to the product label.

References

* In a canine interleukin-31 (cIL-31)-induced pruritus model.† No clinically relevant drug interactions observed during 28-day field trial in dogs with allergic dermatitis after use with antimicrobials (including topicals), ecto- and endoparasiticides (isoxazolines, milbemycins, avermectins, pyrethrins, and pyrethroids), analgesics, anesthetics, nutritional supplements, topical skin and ear cleansers that did not contain glucocorticoids, as well as medicated shampoos.1. Kowalski T, Prohaczik A, Locke K, et al. The second-generation Janus kinase inhibitor atinvicitinib significantly reduces pruritus 2-4 hours after dosing dogs in a canine interleukin-31 model. Vet Dermatol. 2026;0:17-18. https://doi.org/10.1111/vde.700462. Data on File. Study Summary REF-11196. Merck Animal HealthProduct sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.

Indications or Uses: Usage: Numelvi should be given orally, once daily, as prescribed by your veterinarian. Wash your hands thoroughly with soap and water immediately after handling the medication. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. Numelvi should be administered with food. Contact your veterinarian if your pet's condition worsens or does not improve after starting the medication. Additional information may be provided within the manufacturer's full Prescribing Information. Always follow the specific instructions provided by your veterinarian regarding your pet's care.

Pet Type: Dog

Brand Name: NUMELVI

Generic Name: Atinvicitinib

Ingredients: Active Ingredient: Atinvicitinib

Drug Interactions: Drug and food interactionsThere are no clinically relevant drug or food interactions documented for this product.The following drugs* may have potential interactions with this medication: cyclosporine, glucocorticoids (e.g., dexamethasone, prednisone), and other systemic immunosuppressive agents (e.g., mycophenolate).*NOTE: This may not be a comprehensive list. As with all medications, please consult your veterinarian if you have any questions or concerns prior to use. Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

General or Recommended Dosage: Usage Numelvi should be given orally, once daily, as prescribed by your veterinarian. Wash your hands thoroughly with soap and water immediately after handling the medication. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. Numelvi should be administered with food. Contact your veterinarian if your pet's condition worsens or does not improve after starting the medication. Additional information may be provided within the manufacturer's full Prescribing Information. Always follow the specific instructions provided by your veterinarian regarding your pet's care.

Storage Instructions: Storage Store in a cool, dry place at a controlled room temperature (59 to 86°F). Keep NUMELVI in a secure location out of reach of children and animals to prevent accidental ingestion or overdose. Exposure to extreme temperatures, light, or moisture can affect the integrity and effectiveness of medications. Always store this medication properly (e.g., away from the bathroom, kitchen sink, or other damp places).

Potential Side Effects: Side effects As with all drugs, side effects may occur; the most common side effects of this medication are vomiting, nausea, otitis externa (outer ear infection), hematuria (blood in the urine), and decreased appetite. Contact your veterinarian immediately if you notice signs of an infection (e.g., coughing/wheezing, bleeding or oozing skin sores, painful/frequent urination, etc.), any new and abnormal skin changes/growths, or enlargement of existing skin masses. The information provided above may not encompass all possible side effects; for more information, please contact your veterinarian or refer to the manufacturer package insert. Please notify your veterinarian if your pet experiences any side effects, including those listed above, or if you notice anything unusual.