Hot, Spot & Itch Relief

(18596 results)
Live Crickets
2 sizes
(5430)
$0.17
17¢ Each up to 35 Crickets | 16¢ Each on 36+ Crickets | 15¢ Each on 51+ Crickets | 14¢ Each on 76+ Crickets
Spend $250 on reptile terrariums and supplies earn 25,000 points ($50 back in savings)
+ 1 more
Fresh Step Multi-Cat Clumping Litter With Febreze Freshness, Bag, 42 LB
(35049)
$19.99
$27.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Buy 1, Get the 2nd 25% off Fresh Step Cat Litter, 37.5 & 42 lb
+ 3 more
Dr. Elsey's Precious Cat Ultra Clumping Multi-Cat Clay Cat Litter - Unscented, Low Tracking
2 sizes
(2577)
$12.99 - $20.99
Save 35% On Your First Autoship Order!
5X pts (10% back in savings) on ALL litter!
+ 1 more
Purina® Pro Plan Sensitive Skin & Stomach Adult Dry Dog Food - Salmon & Rice, No Corn, Wheat or Soy
4 sizes 1 flavor
(6933)
$20.69 - $94.99
Get 40% OFF your first Purina® Pro Plan® Autoship order,  20% OFF your second order & 10% OFF your third order. Place your first Purina® Pro Plan® Autoship order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 3 more
Fresh Step Simply Unscented Clumping Cat Litter, Bag, 42 LB
(7941)
$18.39
$27.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Buy 1, Get the 2nd 25% off Fresh Step Cat Litter, 37.5 & 42 lb
+ 3 more
Arm & Hammer™ Clump & Seal Slide Clumping Multi-Cat Clay Cat Litter - Low Dust
3 sizes
(5960)
$12.99 - $26.79
Save 15% when you spend $50+ on FREE Same-Day Delivery
Save $2 each when you buy 2+ Arm & Hammer Cat Litter, 38lb
+ 3 more
Purina® Tidy Cats® Free & Clean Natural Clumping Multi-Cat Clay Cat Litter - Unscented, Low Dust
2 sizes
(1790)
$11.49 - $16.59
Get 40% OFF your 1st Tidy Cats® Autoship order,  20% OFF your 2nd & 10% OFF your 3rd. Place your first Tidy Cats® order by 10/12
Save 15% when you spend $50+ on FREE Same-Day Delivery
+ 3 more
Purina® Pro Plan Complete Essentials Shredded Blend Adult Dry Dog Food - Chicken & Rice
4 sizes 1 flavor
(3449)
$16.59 - $96.49
Get 40% OFF your first Purina® Pro Plan® Autoship order,  20% OFF your second order & 10% OFF your third order. Place your first Purina® Pro Plan® Autoship order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 3 more
ExquisiCat Litter Multi-Cat Paper Pellet Cat Litter - Unscented, Low Dust, Low Tracking, Natural
2 sizes
(1816)
$13.99 - $19.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Save 35% On Your First Autoship Order!
+ 2 more
Arm & Hammer Double Duty Cat Litter Deodorizer
(1779)
$3.29
$7.99
Buy 2, Get the 3rd FREE select Dog and Cat Stain & Odor
Save 35% On Your First Autoship Order!
+ 2 more
Authority® Sensitive Stomach & Skin All Life Stages Dry Dog Food - Salmon & Rice
4 sizes 1 flavor
(1369)
$17.99 - $71.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 3 more
World's Best Cat Litter Multiple Cat Clumping Litter - Flushable, 99% Dust Free, Clumping, 28 LB
(7348)
$36.99
$39.99
Save 35% On Your First Autoship Order!
5X pts (10% back in savings) on ALL litter!
+ 1 more
Purina® Fancy Feast® Classic Pate Wet Cat Food - Poultry & Beef, Variety Pack, 3 Oz, 30 Count
(614)
$25.74
$26.40
Save 40% on your 1st Purina or Merrick Autoship Order!
Earn 5,000 points ($10 back in savings) when you spend $40+ on cat food.
+ 1 more
Purina® Fancy Feast® Gravy Lovers Wet Cat Food - Poultry & Beef, Variety Pack, 3 Oz, 30 Count
(271)
$25.74
$26.40
Save 40% on your 1st Purina or Merrick Autoship Order!
Earn 5,000 points ($10 back in savings) when you spend $40+ on cat food.
+ 1 more
ExquisiCat Litter Multi-Cat Pine Pellet Cat Litter - Unscented, Low Dust, Low Tracking, Natural
3 sizes
(2344)
$12.99 - $19.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Save 35% On Your First Autoship Order!
+ 2 more
Hill's® Science Diet® Sensitive Stomach & Skin Adult Dry Dog Food - Chicken & Barley
4 sizes 1 flavor
(1754)
$23.99 - $97.99
Get 35% OFF your 1st Hill's Science Diet® Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first Hill's Science Diet® order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 2 more
Purina® Pro Plan Sensitive Skin & Stomach Adult Dry Dog Food - Lamb & Oat Meal, No Corn, Wheat Soy
3 sizes 1 flavor
(1513)
$20.69 - $77.49
Get 40% OFF your first Purina® Pro Plan® Autoship order,  20% OFF your second order & 10% OFF your third order. Place your first Purina® Pro Plan® Autoship order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 3 more
Top Paw® Ultra XXL Dog Pads - 27.5"L x 44"W
(1257)
$39.99
Buy 1, Get the 2nd 25% ALL Disposable Dog Pads
Save 35% On Your First Autoship Order!
+ 2 more
Simply Nourish® Original Adult Dry Dog Food - Chicken & Brown Rice
4 sizes 1 flavor
(862)
$14.99 - $59.99
Get 40% OFF your 1st Simply Nourish® Autoship order,  20% OFF your 2nd & 10% OFF your 3rd. Place your first Simply Nourish® order by 10/12
Save 15% when you spend $50+ on FREE Same-Day Delivery
+ 3 more
Arm & Hammer™ Clump & Seal Clumping Multi-Cat Clay Cat Litter - Low Dust
3 sizes
(12314)
$12.99 - $26.79
Save 15% when you spend $50+ on FREE Same-Day Delivery
Save $2 each when you buy 2+ Arm & Hammer Cat Litter, 38lb
+ 3 more
Purina® Pro Plan® Veterinary Supplements FortiFlora-Probiotic Powder Supplement for Dogs - 30 Count
(1320)
$30.99
$33.99
Save 40% on your 1st Purina or Merrick Autoship Order!
Get 20% off a Pro Plan Supplement when you buy a bag of Pro Plan dry food or variety pack. Limit 1 per Transaction.
+ 2 more
Hill's® Science Diet® Sensitive Stomach & Skin Adult Wet Dog Food - Turkey & Rice, 12.5 oz
(744)
$4.09
Get 35% OFF your 1st Hill's Science Diet® Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first Hill's Science Diet® order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 1 more
ExquisiCat Litter Premium Clumping Multi-Cat Clay Cat Litter - Unscented, Low Dust
3 sizes
(665)
$9.99 - $17.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Save 35% On Your First Autoship Order!
+ 2 more
Arm & Hammer™ Double Duty Clumping Clay Cat Litter - Scented, Low Dust, Low Tracking
3 sizes
(3247)
$9.99 - $19.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Save 35% On Your First Autoship Order!
+ 2 more
Purina® Tidy Cats® 24/7 Performance Clumping Multi-Cat Clay Cat Litter - Low Dust, 10 Day Odor
2 sizes
(6129)
$11.49 - $19.69
Get 40% OFF your 1st Tidy Cats® Autoship order,  20% OFF your 2nd & 10% OFF your 3rd. Place your first Tidy Cats® order by 10/12
Save 15% when you spend $50+ on FREE Same-Day Delivery
+ 3 more
Simply Nourish® Original Adult Wet Dog Food - 10 Oz., Stew
1 size 2 flavors
(940)
$3.09
Get 40% OFF your 1st Simply Nourish® Autoship order,  20% OFF your 2nd & 10% OFF your 3rd. Place your first Simply Nourish® order by 10/12
Save 15% when you spend $50+ on FREE Same-Day Delivery
+ 3 more
Live Giant Mealworms - 35 Count Cup
(381)
$3.99
Spend $250 on reptile terrariums and supplies earn 25,000 points ($50 back in savings)
Free Same-Day Delivery, No Order Minimum!
Top Paw® X-Large Adhesive Dog Pads - 28" x 34"
(245)
$59.99
Buy 1, Get the 2nd 25% ALL Disposable Dog Pads
Save 35% On Your First Autoship Order!
+ 2 more
Purina Pro Plan Sensitive Skin & Stomach Large Breed Adult Dry Dog Food - Salmon & Rice
2 sizes 1 flavor
(884)
$77.49 - $97.99
Get 40% OFF your first Purina® Pro Plan® Autoship order,  20% OFF your second order & 10% OFF your third order. Place your first Purina® Pro Plan® Autoship order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 3 more
Hill's Science Diet Perfect Weight Adult Dry Dog Food - Chicken
3 sizes 1 flavor
(1158)
$25.99 - $87.99
Get 35% OFF your 1st Hill's Science Diet® Autoship order, 20% OFF your 2nd & 10% OFF your 3rd. Place your first Hill's Science Diet® order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 2 more
Purina Pro Plan Complete Essentials Shredded Blend Adult Dry Dog Food - Salmon & Rice
4 sizes 1 flavor
(1382)
$16.59 - $74.49
Get 40% OFF your first Purina® Pro Plan® Autoship order,  20% OFF your second order & 10% OFF your third order. Place your first Purina® Pro Plan® Autoship order by 10/12
Earn 5,000 points ($10 back in savings) when you spend $60+ on dog food.
+ 3 more
Great Choice® X-Large Dog Pads - 28"L x 30"W
2 sizes
(2222)
$19.99 - $44.99
Buy 1, Get the 2nd 25% ALL Disposable Dog Pads
Save 35% On Your First Autoship Order!
+ 2 more
Simply Nourish® Original Adult Dry Dog Food - Lamb & Oatmeal
3 sizes 1 flavor
(652)
$14.99 - $56.99
Get 40% OFF your 1st Simply Nourish® Autoship order,  20% OFF your 2nd & 10% OFF your 3rd. Place your first Simply Nourish® order by 10/12
Save 15% when you spend $50+ on FREE Same-Day Delivery
+ 3 more
Friskies® Seafood Sensations Adult Cat Dry Food - Seafood
3 sizes 1 flavor
(9075)
$15.99 - $27.49
Save 40% on your 1st Purina or Merrick Autoship Order!
Earn 5,000 points ($10 back in savings) when you spend $40+ on cat food.
+ 2 more
Friskies® Poultry Pate Adult Cat Wet Food - Variety Pack, 5.5 Oz, 32 Count
(660)
$24.59
$24.99
Save 40% on your 1st Purina or Merrick Autoship Order!
Earn 5,000 points ($10 back in savings) when you spend $40+ on cat food.
+ 1 more
Inaba Churu Puree Lickable Cat Treat Variety Pack - Tuna & Chicken, 50 Count
(428)
$32.99
$42.99
Save 15% when you spend $50+ on FREE Same-Day Delivery
Save 35% On Your First Autoship Order!
+ 2 more
Purina® Tidy Cats® Breeze Cat Litter Pellets Refill Pack - Anti Tracking
2 sizes
(765)
$9.78 - $18.18
Buy 2, Get the 3rd 25% off Tidy Cats Breeze Pads & Pellets
Save 35% On Your First Autoship Order!
+ 2 more
Oxbow Western Timothy Hay
6 sizes
(1642)
$5.49 - $76.99
Buy 1 Get the 2nd 25% off all Oxbow Hay
Save 40% on your first Autoship order of Small Pet food, treats, hay and bedding
+ 3 more
Fancy Feast® Kitten Classic Pate Wet Cat Food - Variety Pack, 3 Oz, 24 Count, Real Milk
(3213)
$20.99
$21.19
Save 40% on your 1st Purina or Merrick Autoship Order!
Earn 5,000 points ($10 back in savings) when you spend $40+ on cat food.
+ 1 more
Purina® Tidy Cats® With Glade Multi Cat Clumping Clay Cat Litter - Clear Springs Scent, Low Dust
(4278)
$19.69
$21.49
Get 40% OFF your 1st Tidy Cats® Autoship order,  20% OFF your 2nd & 10% OFF your 3rd. Place your first Tidy Cats® order by 10/12
Save 15% when you spend $50+ on FREE Same-Day Delivery
+ 3 more
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Dog Hot Spot and Itch Relief  

At PetSmart, we understand how uncomfortable itching and hot spots can be for dogs. That’s why we offer a comprehensive range of products designed to soothe your pup’s skin and provide fast relief. From anti itch for dogs to hot spot treatment for dogs, we have everything you need to help your dog feel their best. 
Explore Solutions for Itch and Hot Spot Relief 
Every pup deserves the comfort of itch-free days. Discover a carefully curated collection of dog itch relief solutions that tackle stubborn irritation and soothe sensitive skin. Fast-acting hot spot sprays deliver immediate relief for inflamed or raw areas, while gentle anti-itch creams offer targeted care to ease persistent discomfort. With these innovative treatments, your furry friend can enjoy lasting comfort and a happier, more active life. 
Shop Dog Itch and Hot Spot Relief Products at PetSmart 
At PetSmart, we’re committed to helping you keep your dog happy and comfortable. Explore our range of dog itch relief products, including anti itch creams for dogs, hot spot treatments for dogs, and more. Whether your dog needs a soothing itch cream or a fast-acting spray, you’ll find high-quality solutions to meet their needs. 
Frequently Asked Questions (FAQs) 
What is the most common cause of itching in dogs? 
The most common causes of itching in dogs include allergies (to food, pollen, or fleas), dry skin, and infections. Identifying the cause is key to choosing the right treatment. 
How do I stop my dog’s uncontrollable itching? 
Start with a vet consultation to rule out underlying issues. Then, use products like anti itch cream for dogs, dog anti itch sprays, or hot spot treatments to provide relief. Regular grooming and a balanced diet can also help. 
What to give my dog for itching? 
Over-the-counter options like dog anti itch cream or hot spot spray for dogs can provide immediate relief. For ongoing issues, consult your vet about potential dietary changes or medication. 
Do dogs get hot spots? 
Yes, dogs can develop hot spots that are red, inflamed areas of skin caused by excessive licking, scratching, or moisture trapped in their fur. Hot spot treatment for dogs can soothe and heal these areas quickly.