Fluoxetine - 10 mg, 20 mg, 40 mg - Single Capsule

Description Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant that is used to treat separation anxiety in dogs. Your veterinarian may also prescribe this medication to help treat various behavioral conditions in dogs, cats, and other animal species, including horses and birds.

Fluoxetine has an FDA-approved indication in dogs to treat separation anxiety as part of a behavior modification plan.

This medication may also be used as a supplemental treatment in dogs and cats for a variety of behavioral disorders, including anxiety, compulsive behaviors, and aggression.

Can be used in horses to help facilitate stall rest or to help treat behavioral issues

Used in birds to treat feather picking and other behavior disorders

May be used for other animal species; please consult your veterinarian.

While this medication does not have an FDA-approved indication across all animal uses and species, it is a common and acceptable practice for veterinarians to prescribe this human generic medication for use in animals.

Medications can play a significant role in comprehensive behavior modification therapy. Please follow your pet’s individual treatment plan, which may include a combination of medications and behavioral modification strategies, as recommended by your veterinarian or animal behaviorist.

*Please note: this is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.
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For: Dogs and Cats This product is available in multiple strengths and sizes; please select the appropriate option for your pet as recommended by your veterinarian. For current availability, please refer to the product selection above.

Active ingredient(s) Fluoxetine hydrochloride

Common brand names Prozac®, Reconcile®

Drug class Selective Serotonin Reuptake Inhibitor Antidepressant

Usage: Fluoxetine should be given orally as directed by your veterinarian. While some animals may show improvement within the first week, this medication may require 8 weeks or longer to reach its full therapeutic effect. Your veterinarian may monitor closely and adjust the dosage according to your pet’s treatment plan. Do not discontinue this medication abruptly. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. This medication can be given with or without food. If your pet vomits or appears unwell after receiving a dose on an empty stomach, give future doses with food or a small treat. If vomiting continues, contact your veterinarian. Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.Missed doses

Storage: Store in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep in a tight, light–resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store this medication in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture. Side effects may include (but are not limited to): drowsiness, decreased appetite, stomach upset, vomiting, diarrhea, and restlessness. In rare cases, seizures and aggressive behavior have also been reported. Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome. If you notice anything unusual, please consult your veterinarian. Do not discontinue this medication abruptly without consulting your veterinarian. This medication may not be compatible with certain flea and tick collars; do not use one of these collars concurrently with this medication without consulting your veterinarian first. Use with caution in animals with a history of seizures⁄epilepsy, diabetes, or severe liver issues. Safe use of this medication has not been established in breeding, pregnant, or lactating animals. Do not administer to animals with a known history or suspected allergy⁄hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways, difficulty breathing, agitation, profuse salivation, and widespread hives or itching. The following drugs* may have potential interactions with this medication: acepromazine, alprazolam, amitriptyline, aspirin, clomipramine, clopidogrel, diazepam, diuretics, insulin, monoamine oxidase inhibitors (MAOIs, e.g., selegiline, amitraz, etc), maropitant, metoclopramide, NSAIDs, tramadol, trazodone, and warfarin. *NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely. If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877–738–4443. Last revised: 4⁄03⁄2025