Ursodiol 250 mg - Single Tablet

Usage: Ursodiol Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. This medication works best when given with food, which may also help reduce GI side effects (e.g., nausea) and mask its bitter taste.

Missed Doses: Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.

Side Effects: Ursodiol is usually well–tolerated in dogs and cats. The most common side effects are diarrhea, nausea, and vomiting. Giving this medication with food may help decrease or prevent these effects. Contact your veterinarian immediately if your pet experiences severe vomiting; lowered energy level or weakness; or yellowing of the skin, whites of the eyes, and⁄or gums. Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome. If you notice anything unusual, please consult your veterinarian.

Precautions: This medication should NOT be administered this medication to certain species, including rabbits, guinea pigs, and rodents. These animals metabolize the medication differently, which results in the formation of a toxic substance that can cause serious liver damage and toxicity. Do NOT administer this medication to animals with complete bile duct blockage, or those with a rare liver condition called vanishing bile duct syndrome. Use with caution in animals with certain liver conditions (e.g., cholangitis, cholangiohepatitis) or complications related to gallstones. Safe use of this medication has not been established in breeding, pregnant, or lactating animals. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups. Do not administer to animals with a known history or suspected allergy⁄hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

Drug & Food Interactions: The following drugs* may have potential interactions with this medication: aluminum–containing antacids, cholestyramine, estrogens, fluoroquinolone antibiotics (e.g., ciprofloxacin), and sucralfate. *NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

Overdose: If you have any reason to suspect an overdose, call your doctor⁄veterinarian or the appropriate poison control resource immediately. For humans: The national toll–free Poison Help line, 1–800–222–1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories. For animals: The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888–426–4435. Pet Poison Helpline® also provides a 24⁄7 animal poison control service at 855–764–7661. *Please note: this information is for third–party services and is provided for convenience in case of potential poison–related emergencies. There may be consultation fee for these services.

Storage: Store in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep in a tight, light–resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

Disclaimer: The content provided on this page is NOT medical advice. All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment. Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan. Last revised: 7⁄17⁄2025