DESCRIPTION: Pentosan Polysulfate works to temporarily coat and replenish the glycosaminoglycan (GAG) layer of the urinary bladder. GAGs are responsible for protecting the bladder against urinary agents. This sterile, injectable product also treats osteoarthritis.
Key Benefits:
PPS, or Pentosan Polysulfate, is a heparin-like, semi-synthetic type of polysaccharide ester. It is a beechwood hemicellulose derivative, and it is a mild anticoagulant with anti-inflammatory, fibrinolytic, and hypolipidemic properties. It is used to manage and treat osteoarthritis. It is thought to help preserve cartilage integrity, which improves joint health by supporting chondrocyte and synoviocyte anabolic activity. It protects the joints against catabolic events by reducing inflammatory mediators and cytokine levels in the cartilage matrix and synovial fluid.
Formulated For: Intended for horses, cats and dogs only.
How is Medication Given? Follow your veterinarian's directions when using this product.
What Results Can I Expect? Pentosan Polysulfate coats and replenishes the glycosaminoglycan (GAG) layer of the urinary bladder. It is an effective osteoarthritis treatment option.
What Form Does Medication Come In? Injectable
Dose and Administration: Sold in a vial containing 6 mL (250 mg per mL).
Possible Side Effects: This medication is generally well-tolerated, but potential adverse reactions include: In Horses:
Elevated PTT (partial thromboplastin time), lasting 24 hours or less Intra-articular bleeding (with intra-articular administration)
In Dogs:
Vomiting Anorexia Mild gastrointestinal reactions
Precautions:
Keep away from children and animals. Remove and wash contaminated clothing before reuse. Wear protective gloves, protective clothing, eye protection, and face protection when handling. In case of skin contact, wash thoroughly using plenty of water. If the skin becomes irritated, pursue medical treatment. Wash hands thoroughly after handling. Not FDA-approved.
Storage Recommendations: Store in a cool and dry location.
In Case of Overdose: Contact the nearest emergency pet clinic.
