item: 5276282 By Mycophenolate

Mycophenolate Mofetil Capsule

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$0.75
$0.75
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FREE SHIPPING ON ORDERS OVER $49

Free Standard Shipping on orders over $49. Transaction total is prior to taxes & after discounts are applied. Due to size and/or weight, certain items bear a shipping surcharge or special handling fee, which will still apply. Savings will automatically reflect in shopping cart with the purchase of qualifying merchandise. Maximum value $75. Valid only on orders shipped within the contiguous 48 U.S. states and to military APO/FPO addresses. Offer not valid on products in the following categories: live pets; canned, fresh or frozen foods; select cat litters. Offer may not be combined with other promotional offers or discounts. Terms and conditions of this offer are subject to change at the sole discretion of PetSmart. Offer valid through October 3, 2017 at 6:30 am EST.

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DESCRIPTION: Immunosuppressive drug that may be useful for treating dogs with IMHA, glomerulonephritis, myasthenia gravis, pemphigus foliaceus or inflammatory bowel disease in dogs; potentially useful in cats, but little information available on safety or efficacy.

Benefits: While there has been limited clinical experience using mycophenolate (MMF) in veterinary medicine and no large well-controlled studies were located, it potentially could be useful in the treatment of a variety of autoimmune diseases, including immune-medi

Formulated For: Humans

How is Medication Given? Oral tablets, by mouth

What Results Can I expect? In humans, although it is used "off label" for a variety of automimmune disease indications, the drug is only labeled for use to prevent transplant rejection. Results with use in dogs has been variable; but, has in some cases improved lab values used for monitoring specific autoimmune diseases.

What Form Does Medication Come In? Oral tablets

Generic Name: Mycophenolate mofetil

Common Brand Name: CellCept, Cellmune, Imuxgen

Dose and Administration: Limited dosage information is available. For dogs the dosage range, depending on disease treated, is 10-20 mg/kg twice daily (immune-mediated anemia, glomerular disease, myasthenia gravis & aplastic anemia). A dose of 20 - 40 mg/kg was used 3 times a day for dogs with pemphigus foliaceus. One study in cats with immune-mediated anemia, used the dosage was 10 mg/kg twice daily.

Uses: While there has been limited clinical experience using mycophenolate (MMF) in veterinary medicine and no large well-controlled studies were located, it potentially could be useful in the treatment of a variety of autoimmune diseases, including immune-mediated hemolytic anemia (IMHA), myasthenia gravis, glomerulonephritis, and pemphigus foliaceous. While mycophenolate has been suggested for use in treating inflammatory bowel disease in dogs, the drug’s primary adverse effects in dogs are gastritis, diarrhea, and intestinal inflammation, which may be problematic. Mycophenolate is also used in anti-rejection protocols for organ transplants in animals.

Possible Side Effects: Gastrointestinal effects (diarrhea, vomiting, anorexia) most likely adverse effects & can be severe. If diarrhea persists or is severe, contact veterinarian.

Drug and Food Interactions: The following drug interactions have either been reported or are theoretical in humans or animals receiving mycophenolate mofetil and may be of significance in veterinary patients. Unless otherwise noted, use together is not necessarily contraindicated, but weigh the potential risks and perform additional monitoring when appropriate. Acyclovir: Increased serum concentrations of acyclovir and the phenolic glucuronide of mycophenolic acid. Aminoglycosides (e.g., gentamicin, amikacin): In rats, use together induced greater nephrotoxicity. Antacids (aluminum or magnesium containing): Decreased absorption of mycophenolate; separate dosing by at least 2 hours. Aspirin(or other salicylates): Potentially increased concentrations of free mycophenolic acid. Azathioprine: Increased risk for bone marrow suppression; use together not recommended in humans. Iron (oral): Decreased absorption of mycophenolate; separate dosing by at least 2 hours. Probenecid: Potentially increased serum levels of mycophenolic acid and the phenolic glucuronide of mycophenolic acid. Vaccines (live virus): May be less effective; avoid use.

Precautions: Very limited experience in veterinary medicine, especially in cats or for long-term use. Do not use in patients with documented hypersensitivity reactions to mycophenolate. Patients with severe renal dysfunction may require dosage adjustment. Because MMF can cause diarrhea, use with caution in patients with inflammatory bowel disease. Because of concerns that this drug can cause birth defects, the manufacturer recommends that tablets or capsules not be crushed, split, or opened.

Storage Recommendations: Mycophenolate mofetil capsules should be stored between 15-30 degrees C and protected from light.

Is Prescription from a Vet Required? Yes

Mycophenolate Mofetil Capsule
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